Table 2 Diagnostic test accuracy of procalcitonin for diagnosing serious infection
PCT ng/ml | Sensitivity (95% CI) | Specificity (95% CI) | Negative Predictive Value (95% CI) | Positive Predictive Value (95% CI) | Negative Likelihood Ratio (95% CI) | Positive Likelihood Ratio (95% CI) |
|---|---|---|---|---|---|---|
0.25 | 0.80(0.44 to 0.96) | 0.62(0.55 to 0.69) | 0.98(0.93 to 1.00) | 0.10(0.05 to 0.19) | 0.32(0.09 to 1.12) | 2.12(0.48 to 3.00) |
0.50 | 0.70(0.35 to 0.92) | 0.65(0.58 to 0.72) | 0.98(0.93 to 1.00) | 0.10(0.05 to 0.19) | 0.46(0.18 to 1.19) | 2.02(1.28 to 3.16) |
0.75 | 0.60(0.27 to 0.86) | 0.81(0.74 to 0.86) | 0.98(0.93 to 0.99) | 0.14(0.06 to 0.29) | 0.49(0.23 to 1.06) | 3.13(1.75 to 5.61) |
1.00 | 0.60(0.27 to 0.86) | 0.84(0.78 to 0.89) | 0.98(0.93 to 0.99) | 0.16(0.07 to 0.33) | 0.48(0.22 to 1.02) | 3.74(2.05 to 6.81) |
1.25 | 0.60(0.27 to 0.86) | 0.88(0.82 to 0.92) | 0.98(0.93 to 0.99) | 0.20(0.08 to 0.39) | 0.46(0.21 to 0.98) | 4.83(2.57 to 9.05) |
1.50 | 0.60(0.27 to 0.86) | 0.88(0.82 to 0.92) | 0.98(0.93 to 0.99) | 0.21(0.09 to 0.40) | 0.45(0.21 to 0.97) | 5.03(2.67 to 9.50) |
1.75 | 0.50(0.20 to 0.80) | 0.91(0.85 to 0.94) | 0.97(0.93 to 0.99) | 0.22(0.08 to 0.44) | 0.55(0.30 to 1.03) | 5.36(2.51 to 11.46) |
2.00 | 0.40(0.14 to 0.73) | 0.92(0.87 to 0.95) | 0.97(0.93 to 0.99) | 0.20(0.07 to 0.44) | 0.65(0.39 to 1.09) | 4.83(1.98 to 11.80) |