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Table 1 Odds ratios for neonatal morbidity and mortality for neonates born with Down syndrome or chromosomal disorders other than Down syndrome

From: The risks of advancing parental age on neonatal morbidity and mortality are U- or J-shaped for both maternal and paternal ages

  Odds ratio for Down syndrome Odds ratio for chromosomal disorders1
Preterm Delivery 4.2 (4.0, 4.4) 6.0 (5.6, 6.4)
Very preterm delivery 2.8 (2.4, 3,2) 8.1 (7.3, 9.0)
Small for gestational age 2.3 (2.2, 2.4) 5.2 (4.9, 5.5)
Low Apgar score 4.7 (4.0, 5.6) 31.4 (28.7, 34.1)
Admission to NICU 15.7 (15.0, 16.5) 15.9 (15.0, 16.8)
Antibiotics 7.8 (7.3, 8.3) 11.4 (10.6, 12.3)
Surfactant 6.0 (5.0, 7.1) 16.4 (14.4, 18.6)
Prolonged ventilation 12.7 (11.7, 13.7) 22.9 (21.3, 24.6)
Seizure(s) 11.7 (7.7, 17.0) 49.7 (39.0, 62.5)
Death 12.6 (11.1, 14.3) 70.2 (65.0, 75.7)
  1. 1 Chromosomal disorders other than Down syndrome