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Table 1 Odds ratios for neonatal morbidity and mortality for neonates born with Down syndrome or chromosomal disorders other than Down syndrome

From: The risks of advancing parental age on neonatal morbidity and mortality are U- or J-shaped for both maternal and paternal ages

 

Odds ratio for Down syndrome

Odds ratio for chromosomal disorders1

Preterm Delivery

4.2 (4.0, 4.4)

6.0 (5.6, 6.4)

Very preterm delivery

2.8 (2.4, 3,2)

8.1 (7.3, 9.0)

Small for gestational age

2.3 (2.2, 2.4)

5.2 (4.9, 5.5)

Low Apgar score

4.7 (4.0, 5.6)

31.4 (28.7, 34.1)

Admission to NICU

15.7 (15.0, 16.5)

15.9 (15.0, 16.8)

Antibiotics

7.8 (7.3, 8.3)

11.4 (10.6, 12.3)

Surfactant

6.0 (5.0, 7.1)

16.4 (14.4, 18.6)

Prolonged ventilation

12.7 (11.7, 13.7)

22.9 (21.3, 24.6)

Seizure(s)

11.7 (7.7, 17.0)

49.7 (39.0, 62.5)

Death

12.6 (11.1, 14.3)

70.2 (65.0, 75.7)

  1. 1 Chromosomal disorders other than Down syndrome