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Table 2 Linear regression modelling of cytokine levels at study start (baseline) and stimulated C-peptide (log transformed) at 6 and 12 months

From: Systemic TNFα correlates with residual β-cell function in children and adolescents newly diagnosed with type 1 diabetes

Baseline cytokines association to: C-peptide at 6 months, adjusted for sex, age, HbA1c and Tanner C-peptide at 12 months adjusted for sex, age, HbA1c and Tanner
Predictor Outcome
Intercept CI (5–95%)
P-value Outcome
Intercept CI (5–95%)
P-value
IFN-γ -0.03 (-0.1; 0) 0.507 0.03 (0; 0.1) 0.451
IL-10 -0.57 (-1; -0.1) 0.043 0.23 (-0.2; 0.7) 0.384
IL-12p70 -1.85 (-3.8; 0.1) 0.122 -1.23 (-2.7; 0.2) 0.165
IL-2 -0.66 (-1.8; 0.5) 0.333 0.3 (-0.8; 1.4) 0.640
IL-4 -10.3 (-19.5; -1.1) 0.069 6.64 (-4.8; 18.1) 0.328
IL-6 -0.38 (-0.77; 0) 0.117 0.14 (-0.2; 0.5) 0.514
IL-8 0.03 (-0.1; 0.2) 0.620 -0.05 (-0.2; 0.1) 0.535
TNFα -0.38 (-0.6; -0.1) 0.011 0 (-0.2; 0.2) 0.976