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Table 3 Differences in development milestones gains between children with severe Zika-related Microcephaly, divided by age groups, using the SWYC adapted form

From: Pediatric neurodevelopment by prenatal Zika virus exposure: a cross-sectional study of the Microcephaly Epidemic Research Group Cohort

Development Milestones

≤ 24 months (n = 29)

> 24 months (n = 82)

 

Not yet

Some what

Very much

Mean Rank

Not yet

Some what

Very much

Mean Rank

P Valuea

Makes sounds that let you know he or she is happy or upset

0

6

23

53.5

5

6

71

56.9

0.44

Seems happy to see you

1

2

26

54.8

2

4

76

56.4

0.61

Follows a moving toy with his or her eyes

5

10

14

50.3

7

26

49

58.0

0.21

Turns head to find the person who is talking

0

9

20

53.5

5

14

63

56.9

0.53

Holds head steady when being pulled up to a sitting position

9

12

8

54.3

25

30

27

56.6

0.73

Brings hands together

14

6

9

53.9

40

8

34

56.7

0.66

Laughs

1

5

23

50.2

3

2

77

58.0

0.03

Keeps head steady when held in a sitting position

9

14

6

50.3

19

37

26

58.0

0.23

Makes sounds like “ga,“ “ma,“ or “ba”

19

4

6

51.0

46

8

28

57.8

0.27

Looks when you call his or her name

3

9

17

50.3

7

15

60

58.0

0.17

Rolls over

16

8

5

52.4

42

16

24

57.3

0.45

Passes a toy from one hand to the other

26

0

3

52.9

67

4

11

57.1

0.35

Looks for you or another caregiver when upset

7

8

14

56.2

30

6

46

55.9

0.96

Holds two objects and bangs them together

26

1

2

54.7

71

3

8

56.5

0.66

Holds up arms to be picked up

26

2

1

50.8

64

4

14

57.8

0.14

Gets into a sitting position by him or herself

28

1

0

52.3

72

1

9

57.3

0.16

Picks up food and eats it

24

1

4

56.6

69

3

10

55.8

0.85

Pulls up to standing

25

4

0

52.0

65

1

16

57.4

0.26

Plays games like “peekaboo” or “patacake”

24

3

2

55.0

67

2

13

56.4

0.76

Calls you “mama” or “dada” or similar name

26

2

1

53.3

69

0

13

57.0

0.39

Looks around when you say things like “Where’s your bottle?“ or “Where’s your blanket?“

24

4

1

52.8

64

0

18

57.1

0.38

Copies sounds that you make

26

1

2

52.9

67

9

6

57.1

0.35

Walks across a room without help

29

0

0

53.5

77

0

5

56.9

0.18

Follows directions like “Come here” or “give me the ball”

28

1

0

51.8

71

4

7

57.5

0.13

Runs

29

0

0

53.5

77

0

5

56.9

0.18

Walks upstairs with help

28

0

1

55.4

78

0

4

56.2

0.75

Kicks a ball

27

2

0

57.8

80

0

2

55.4

0.29

Names at least 5 familiar objects like ball or milk

28

0

1

54.9

77

1

4

56.4

0.59

Names at least 5 body parts like nose, hand, or tummy

29

0

0

55.5

81

0

1

56.2

0.55

Climbs up a ladder at a playground

28

1

0

55.3

78

0

4

56.2

0.72

Uses words like “me” or “mine”

28

1

0

55.9

79

0

3

56.0

0.93

Jumps off the ground with two feet

28

1

0

55.9

79

0

3

56.0

0.93

Puts 2 or more words together like “more water” or “go outside”

29

0

0

55.0

80

1

1

56.3

0.40

Uses words to ask for help

28

1

0

55.4

78

1

3

56.2

0.73

  1. a Mann-Whitney U test