Table 1 Birth characteristics, neurological and radiological characteristics of groups of infants with severe and moderate Zika related microcephaly, as well as those exposed and neurotypical controls
Biological and radiological characteristics | Study Groups | ||||
|---|---|---|---|---|---|
Group 1 | Group 2 | Group 3 | Group 4 | ||
Severe Microcephaly (n = 114) | Moderate microcephaly (n = 20) | ZIKV maternal infection a (n = 94) | Controls b (n = 46) | P Value | |
Sex, No. (%) | |||||
Female | 64 (56.1) | 12 (60.0) | 47 (50.0) | 25 (54.3) | .786 |
Male | 50 (43.9) | 8 (40.0) | 47 (50.0) | 21 (45.7) | |
Prematurity, Weeks of Gestational Age, No. (%) | |||||
< 37 | 16 (14.2) | 4 (25.0) | 6 (7.9) | 7 (15.2) | .249 |
≥ 37 | 97 (85.8) | 12 (75.0) | 70 (92.1) | 39 (84.8) | |
Missing | 1 | 4 | 18 | 0 | |
Birthweight, g, No. (%) | |||||
< 2500 | 28 (25.5) | 10 (58.8)c | 5 (7.1) | 2 (4.3) | < 0.001 |
2500–2999 | 47 (42.7) | 3 (17.6) | 14 (20.0) | 12 (26.1) | |
≥ 3000 | 35 (31.8) | 32 (69.6) | |||
Missing | 4 | 3 | 4 (23.5) | 51 (72.9) | |
Small-for-gestational age, No. (%) | |||||
Yes | 29 (26.4) | 8 (47.1)c | 5 (7.1) | 2 (4.3) | < 0.001 |
No | 81 (73.6) | 9 (52.9) | 65 (92.9) | 44 (95.7) | |
Missing | 4 | 3 | 24 | 0 | |
Clinical neurological abnormalities, No. (%) | |||||
Yes | 112 (98.2)c | 12 (60.0) | 10 (11.1) | 3 (7.5) | < 0.001 |
No | 2 (1.8) | 8 (40.0) | 80 (88.9) | 37 (92.5) | |
Missing | 0 | 0 | 4 | 6 | |
Neuroimaging abnormalities, No. (%) | |||||
Yes | 103 (97.2)c | 6 (37.5) | 5 (11.6) | 0 (0) | < 0.001 |
No | 3 (2.8) | 10 (62.5) | 38 (88.4)d | 46 (100) | |
Missing | 8 | 4 | 51 | 0 | |