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Table 2 Characteristics of included studies for MTHFR A1298C polymorphism

From: Association between MTHFR C677T/A1298C and susceptibility to autism spectrum disorders: a meta-analysis

Author, year Quality Score Country Ethnicity Case Control Sample source Folate HWE
N AA AC CC N AA AC CC
Boris et al. 2004 [22] 6 USA Caucasian 168 93 65 10 159 70 75 14 Hospital-based YES 0
James et al. 2006 [43] 7 USA Caucasian 356 175 147 34 204 103 77 24 Hospital-based YES 0.974
Mohammad et al. 2009 [35] 7 USA Asian 138 35 59 44 138 48 32 58 Population-based NO 0.412
Liu et al. 2011 [44] 8 Canada Caucasian 205 109 81 15 382 170 175 37 Population-based YES 0.823
Liu et al. 2011 [44] 7 Canada Caucasian 307 134 133 40 382 170 175 37 Population-based YES 0.823
Schmidt et al. 2011 [45] 8 USA Caucasian 296 160 117 19 177 89 76 12 Population-based YES 0.241
Park et al. 2014 [47] 6 Korea Asian 236 147 75 14 323 198 114 11 Hospital-based NO 0.737
Meguid et al. 2015 [49] 8 Egypt Caucasian 24 0 23 1 30 12 16 2 Population-based NO 0.361
El-baz et al. 2017 [32] 6 Egypt Caucasian 31 7 13 11 39 31 7 1 Hospital-based YES 0.451
Zhao et al. 2013 [36] 9 China Asian 200 144 19 37 200 166 21 13 Hospital-based NO 0