From: Vitamin D supplementation in obese Sri Lankan children: a randomized controlled trial
Parameter | Supplementation (n = 33) | Treatment (n = 32) | Placebo (n = 31) | Sig**. | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Baseline | 6 months | Sig*. | Baseline | 6 months | Sig*. | Baseline | 6 months | Sig*. | ||
Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | |||||
Height SDS | 0.64 (1.53) | 0.34 (1.38) | 0.362 | 0.66 (1.09) | 0.70 (1.07) | 0.535 | 0.50 (1.32) | 0.45 (1.29) | 0.194 | 0.581 |
BMI SDS | 2.83 (0.86) | 2.70 (0.85) | 0.142 | 2.72 (0.65) | 2.52 (0.79) | 0.021 | 2.66 (0.55) | 2.57 (0.51) | 0.073 | 0.297 |
WC SDS | 3.22 (0.72) | 2.89 (0.74) | 0.006 | 3.04 (0.62) | 2.75 (0.73) | 0.003 | 2.9 (0.56) | 2.69 (0.50) | 0.000 | 0.369 |
Triceps SFT (cm) | 26.93 (5.1) | 26.04 (5.8) | 0.415 | 27.36 (5.2) | 24.88 (5.3) | 0.003 | 27.05 (4.5) | 25.48 (4.9) | 0.117 | 0.548 |
Biceps SFT (cm) | 20.65 (5.2) | 20.26 (5.25) | 0.725 | 19.69 (6.2) | 17.75 (5.1) | 0.065 | 19.56 (4.7) | 20.1 (5.9) | 0.547 | 0.121 |
Subscapular SFT (cm) | 32.63 (8.6) | 33.5 (8.6) | 0.567 | 31.29 (7.3) | 30.31 (7.3) | 0.389 | 29.45 (5.3) | 32.54 (6.6) | 0.006 | 0.212 |
Suprailiac SFT (cm) | 31.08 (6.6) | 33.34 (6.4) | 0.112 | 31.23 (5.9) | 30.92 (6.1) | 0.681 | 30.94 (5.9) | 33.54 (5.4) | 0.058 | 0.179 |
SBP SDS | −1.33 (0.82) | −1.26 (0.85) | 0.685 | −1.29 (0.78) | −1.236 (0.98) | 0.786 | −1.41 (0.87) | −1.16 (0.85) | 0.256 | 0.863 |
DBP SDS | 0.86 (0.77) | 0.82 (.716) | 0.834 | 0.82 (.645) | 0.73 (.699) | 0.562 | 0.94 (0.68) | 0.97 (0.698) | 0.842 | 0.447 |
Percentage FM | 43.31 (4.95) | 41.29 (5.46) | 0.000 | 41.89 (4.068) | 38.75 (5.7) | 0.001 | 41.94 (4.31) | 39.76 (5.43) | 0.008 | 0.152 |
Vitamin D (ng/ml) | 14.92 (3.92) | 15.26 (3.675) | 0.505 | 14.92 (3.04) | 18.24 (5.77) | 0.003 | 15.47 (2.78) | 15.77 (3.43) | 0.579 | 0.020 |
PTH (pg/ml) | 36.41 (21.47) | 33.94 (21.94) | 0.325 | 37.24 (18.13) | 30.64 (19.69) | 0.006 | 34.19 (15.37) | 29.23 (15.29) | 0.137 | 0.648 |
FBS (mg/dl) | 86.18 (8.62) | 88.00 (7.79) | 0.291 | 83.19 (5.28) | 90.23 (8.82) | 0.000 | 83.50 (6.17) | 92.90 (11.15) | 0.000 | 0.125 |
OGTT (mg/dl) | 119.25 (21.08) | 119.91 (17.79) | 0.861 | 112.48 (18.84) | 117.77 (25.43) | 0.240 | 116.63 (21.81) | 123.23 (19.48) | 0.052 | 0.565 |
Fasting Insulin (μIU/ml) | 15.87 (8.96) | 14.09 (7.97) | 0.198 | 12.86 (8.58) | 15.19 (17.76) | 0.406 | 12.16 (8.47) | 13.312 (6.80) | 0.364 | 0.854 |
2-h Insulin (μIU/ml) | 118.60 (85.32) | 115.57 (97.49) | 0.847 | 109.096 (88.2) | 94.89 (91.56) | 0.496 | 111.947 (87.97) | 94.70 (74.76) | 0.092 | 0.581 |
Total cholesterol (mg/dl) | 198.27 (39.39)) | 201.64 (43.37) | 0.438 | 183.94 (35.09) | 186.09 (38.59) | 0.656 | 176.98 (41.26) | 194.06 (32.64) | 0.034 | 0.398 |
Triglycerides (mg/dl) | 108.36 (46.76) | 120.30 (53.79) | 0.176 | 103.53 (57.79) | 106.13 (61.20) | 0.728 | 129.16 (67.57) | 131.16 (74.84) | 0.844 | 0.299 |
HDL (mg/dl) | 38.48 (7.28) | 45.61 (12.1) | 0.005 | 41.53 (10.22) | 49.25 (15.17) | 0.000 | 41.55 (9.59) | 48.65 (12.06) | 0.000 | 0.392 |
LDL (mg/dl) | 138.11 (33.62) | 132.77 (39.81) | 0.176 | 123.11 (32.24) | 115.64 (33.67) | 0.075 | 115.63 (29.11) | 117.70 (30.34) | 0.658 | 0.134 |
AST (IU/l) | 31.88 (10.29) | 29.24 (8.25) | 0.075 | 38.38 (31.85) | 31.19 (13.28) | 0.075 | 31.45 (15.38) | 31.71 (13.81) | 0.883 | 0.706 |
ALT (IU/l) | 33.72 (21.39) | 25.97 (9.40) | 0.035 | 39.22 (51.37) | 21.66 (9.47) | 0.036 | 29.42 (27.73) | 26.94 (14.27) | 0.543 | 0.142 |
AST/ALT | 1.1764 (0.68) | 1.1957 (0.34) | 0.861 | 1.39 (0.71) | 1.55 (0.59) | 0.195 | 1.38 (.77) | 1.283 (0.38) | 0.499 | 0.011 |
ALP (IU/L) | 262.79 (87.27) | 240.52 (66.28) | 0.008 | 243.0 (56.27) | 231.0 (58.99) | 0.099 | 270.29 (74.72) | 240.39 (70.61) | 0.009 | 0.796 |
HS-CRP (mg/l) | 4.41 (3.53) | 4.22 (3.7) | 0.687 | 3.83 (4.36) | 3.30 (4.26) | 0.426 | 3.562 (3.13) | 4.23 (5.09) | 0.483 | 0.750 |
Serum Ca (mg/dl) | 9.64 (0.46) | 9.44 (0.53) | 0.034 | 9.72 (0.48) | 9.44 (0.51) | 0.013 | 9.71 (0.58) | 9.36 (0.61) | 0.013 | 0.819 |
HOMA IR | 3.45 (2.12) | 3.099 (1.8838) | 0.264 | 2.598 (1.79) | 3.56 (4.96) | 0.242 | 2.529 (1.81) | 3.05 (1.66) | 0.107 | 0.819 |