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Table 2 Anthropometric and Metabolic Parameters at baseline and 6 months in the three intervention arms (n = 96)

From: Vitamin D supplementation in obese Sri Lankan children: a randomized controlled trial

Parameter

Supplementation (n = 33)

Treatment (n = 32)

Placebo (n = 31)

Sig**.

Baseline

6 months

Sig*.

Baseline

6 months

Sig*.

Baseline

6 months

Sig*.

 

Mean (SD)

Mean (SD)

Mean (SD)

Mean (SD)

Mean (SD)

Mean (SD)

Height SDS

0.64 (1.53)

0.34 (1.38)

0.362

0.66 (1.09)

0.70 (1.07)

0.535

0.50 (1.32)

0.45 (1.29)

0.194

0.581

BMI SDS

2.83 (0.86)

2.70 (0.85)

0.142

2.72 (0.65)

2.52 (0.79)

0.021

2.66 (0.55)

2.57 (0.51)

0.073

0.297

WC SDS

3.22 (0.72)

2.89 (0.74)

0.006

3.04 (0.62)

2.75 (0.73)

0.003

2.9 (0.56)

2.69 (0.50)

0.000

0.369

Triceps SFT (cm)

26.93 (5.1)

26.04 (5.8)

0.415

27.36 (5.2)

24.88 (5.3)

0.003

27.05 (4.5)

25.48 (4.9)

0.117

0.548

Biceps SFT (cm)

20.65 (5.2)

20.26 (5.25)

0.725

19.69 (6.2)

17.75 (5.1)

0.065

19.56 (4.7)

20.1 (5.9)

0.547

0.121

Subscapular SFT (cm)

32.63 (8.6)

33.5 (8.6)

0.567

31.29 (7.3)

30.31 (7.3)

0.389

29.45 (5.3)

32.54 (6.6)

0.006

0.212

Suprailiac SFT (cm)

31.08 (6.6)

33.34 (6.4)

0.112

31.23 (5.9)

30.92 (6.1)

0.681

30.94 (5.9)

33.54 (5.4)

0.058

0.179

SBP SDS

−1.33 (0.82)

−1.26 (0.85)

0.685

−1.29 (0.78)

−1.236 (0.98)

0.786

−1.41 (0.87)

−1.16 (0.85)

0.256

0.863

DBP SDS

0.86 (0.77)

0.82 (.716)

0.834

0.82 (.645)

0.73 (.699)

0.562

0.94 (0.68)

0.97 (0.698)

0.842

0.447

Percentage FM

43.31 (4.95)

41.29 (5.46)

0.000

41.89 (4.068)

38.75 (5.7)

0.001

41.94 (4.31)

39.76 (5.43)

0.008

0.152

Vitamin D (ng/ml)

14.92 (3.92)

15.26 (3.675)

0.505

14.92 (3.04)

18.24 (5.77)

0.003

15.47 (2.78)

15.77 (3.43)

0.579

0.020

PTH (pg/ml)

36.41 (21.47)

33.94 (21.94)

0.325

37.24 (18.13)

30.64 (19.69)

0.006

34.19 (15.37)

29.23 (15.29)

0.137

0.648

FBS (mg/dl)

86.18 (8.62)

88.00 (7.79)

0.291

83.19 (5.28)

90.23 (8.82)

0.000

83.50 (6.17)

92.90 (11.15)

0.000

0.125

OGTT (mg/dl)

119.25 (21.08)

119.91 (17.79)

0.861

112.48 (18.84)

117.77 (25.43)

0.240

116.63 (21.81)

123.23 (19.48)

0.052

0.565

Fasting Insulin (μIU/ml)

15.87 (8.96)

14.09 (7.97)

0.198

12.86 (8.58)

15.19 (17.76)

0.406

12.16 (8.47)

13.312 (6.80)

0.364

0.854

2-h Insulin (μIU/ml)

118.60 (85.32)

115.57 (97.49)

0.847

109.096 (88.2)

94.89 (91.56)

0.496

111.947 (87.97)

94.70 (74.76)

0.092

0.581

Total cholesterol (mg/dl)

198.27 (39.39))

201.64 (43.37)

0.438

183.94 (35.09)

186.09 (38.59)

0.656

176.98 (41.26)

194.06 (32.64)

0.034

0.398

Triglycerides (mg/dl)

108.36 (46.76)

120.30 (53.79)

0.176

103.53 (57.79)

106.13 (61.20)

0.728

129.16 (67.57)

131.16 (74.84)

0.844

0.299

HDL (mg/dl)

38.48 (7.28)

45.61 (12.1)

0.005

41.53 (10.22)

49.25 (15.17)

0.000

41.55 (9.59)

48.65 (12.06)

0.000

0.392

LDL (mg/dl)

138.11 (33.62)

132.77 (39.81)

0.176

123.11 (32.24)

115.64 (33.67)

0.075

115.63 (29.11)

117.70 (30.34)

0.658

0.134

AST (IU/l)

31.88 (10.29)

29.24 (8.25)

0.075

38.38 (31.85)

31.19 (13.28)

0.075

31.45 (15.38)

31.71 (13.81)

0.883

0.706

ALT (IU/l)

33.72 (21.39)

25.97 (9.40)

0.035

39.22 (51.37)

21.66 (9.47)

0.036

29.42 (27.73)

26.94 (14.27)

0.543

0.142

AST/ALT

1.1764 (0.68)

1.1957 (0.34)

0.861

1.39 (0.71)

1.55 (0.59)

0.195

1.38 (.77)

1.283 (0.38)

0.499

0.011

ALP (IU/L)

262.79 (87.27)

240.52 (66.28)

0.008

243.0 (56.27)

231.0 (58.99)

0.099

270.29 (74.72)

240.39 (70.61)

0.009

0.796

HS-CRP (mg/l)

4.41 (3.53)

4.22 (3.7)

0.687

3.83 (4.36)

3.30 (4.26)

0.426

3.562 (3.13)

4.23 (5.09)

0.483

0.750

Serum Ca (mg/dl)

9.64 (0.46)

9.44 (0.53)

0.034

9.72 (0.48)

9.44 (0.51)

0.013

9.71 (0.58)

9.36 (0.61)

0.013

0.819

HOMA IR

3.45 (2.12)

3.099 (1.8838)

0.264

2.598 (1.79)

3.56 (4.96)

0.242

2.529 (1.81)

3.05 (1.66)

0.107

0.819

  1. *Significance for the mean difference from baseline to 6 months – Paired samples T test **Significance between groups mean differences at 6 months – One way ANOVA test
  2. BMI Body mass index, WC Waist circumference, SDS SD score, SBP Systolic Blood Pressure, DBP Diastolic Blood Pressure, OGTT Oral glucose tolerance test, PTH Parathyroid hormone, FBS Fasting Blood Sugar, HDL High-density Lipoprotein, LDL Low-density lipoprotein, AST Aspartate transaminase, ALT Alanine transaminase, ALP Alkaline phosphatase, Hs-CRS High sensitivity C reactive protein, FM Fat mass, HOMA-IR Insulin Resistance using homeostatic model