Table 1 Baseline characteristics of the study population
LISA (n = 169) | Control (n = 155) | p-value | |
|---|---|---|---|
GA (weeks + days), mean (SD in days) | 28 + 0 (14) | 28 + 1 (14) | 0.52 |
GA categories | 0.26 | ||
24–25 + 6 weeks | 29 (17.2%) | 21 (13.5%) | |
26–27 + 6 weeks | 58 (34.3%) | 50 (32.3%) | |
28–31 + 6 weeks | 82 (48.5%) | 84 (54.2%) | |
Birth weight (grams), mean (SD) | 1092 (341) | 1130 (350) | 0.33 |
Birth weight categories | 0.44 | ||
< 750 g | 29 (17.2%) | 22 (14.2%) | |
750 - 999 g | 50 (29.6%) | 43 (27.7%) | |
1000 - 1249 g | 34 (20.1%) | 36 (23.2%) | |
≥ 1250 g | 56 (33.1%) | 54 (34.8%) | |
Male sex | 94 (55.6%) | 84 (54.2%) | 0.80 |
Antenatal corticosteroids | 0.82 | ||
None | 8 (4.7%) | 9 (5.8%) | |
Not completed | 53 (31.4%) | 43 (27.7%) | |
Completed | 108 (63.9%) | 103 (66.5%) | |
GA (weeks+days) per category of corticosteroids, mean (SD) | |||
None | 27 + 3 (13) | 28 + 0 (10) | 0.44 |
Not completed | 28 + 2 (14) | 28 + 5 (15) | 0.21 |
Completed | 27 + 6 (15) | 27 + 6 (14) | 0.83 |
Apgar, median (IQR) | |||
1 min | 6 (4.0–6.5) | 5 (4–7) | 0.89 |
5 min | 7 (6–8) | 7 (6–8) | 0.70 |
Umbilical cord pH, median (IQR) | 7.30 (7.26–7.34) | 7.30 (7.24–7.34) | 0.48 |
Maximal FiO2 before SF, median (IQR) | 35 (30–45) | 40 (33.75–50) | 0.15 |
Time birth-SF (hours), median (IQR) | 2 (1.5–3.75) | 2.5 (2–5) | 0.001* |