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Table 2 Agreement of child self-reports and family proxy-reports of pediatric health-related quality of life (N = 522)

From: Comparison of child and family reports of health-related quality of life in pediatric acute lymphoblastic leukemia patients after induction therapy

   n Child
self-reports
Family
proxy-reports
Diffencesa) t-valueb) 95% CI
for Differences
(lower) (upper)
ICCC) 95% CI
for ICC
(lower) (upper)
PedsQL-G (Generic Core Scales)
 Physical functioning All Children 518 54.4 ± 25.5 45.0 ± 26.2 9.3 9.64 7.4 11.2 .60 .47 .70
  Young Child 204 56.9 ± 24.5 47.4 ± 27.3 9.3 6.08 6.3 12.3 .61 .45 .72
  School age 212 53.0 ± 26.9 44.7 ± 26.4 8.2 5.18 5.1 11.3 .60 .47 .70
  Adolescent 102 52.7 ± 24.1 41.1 ± 23.1 11.6 5.88 7.7 15.6 .58 .30 .73
 Emotional functioning All Children 518 68.6 ± 26.1 63.2 ± 24.9 5.4 4.84 3.2 7.6 .49 .42 .56
  Young Child 204 64.3 ± 27.2 65.8 ± 25.4 −1.3 −0.71 −5.1 2.4 .48 .36 .58
  School age 212 72.2 ± 24.9 62.1 ± 25.7 10.0 5.98 6.7 13.3 .50 .35 .62
  Adolescent 102 69.9 ± 25.1 60.5 ± 21.6 9.4 4.39 5.1 13.6 .54 .34 .68
 Social functioning All Children 494 84.5 ± 18.3 82.0 ± 21.4 2.7 2.76 0.8 4.6 .41 .33 .48
  Young Child 193 81.8 ± 18.2 82.7 ± 21.0 −0.8 −0.51 −3.9 2.3 .40 .28 .51
  School age 209 86.8 ± 17.9 80.6 ± 22.4 6.3 4.37 3.4 9.1 .46 .34 .57
  Adolescent 92 85.4 ± 18.5 83.8 ± 20.2 1.9 0.80 −2.8 6.6 .32 .12 .49
 School functioning All Children 391 75.1 ± 27.2 74.5 ± 26.0 1.3 1.02 −1.2 3.7 .55 .48 .61
  Young Child 119 63.8 ± 31.0 78.1 ± 25.4 −12.2 −5.45 − 16.7 −7.8 .56 .35 .71
  School age 196 82.7 ± 21.9 75.0 ± 25.7 7.2 4.61 4.1 10.3 .54 .41 .65
  Adolescent 76 74.4 ± 26.6 66.6 ± 21.6 7.2 2.60 1.7 12.7 .57 .40 .71
PedsQL-C (Cancer Module)
 Pain and hurt All Children 521 74.6 ± 31.3 71.1 ± 29.9 3.5 2.87 1.1 5.9 .59 .53 .64
  Young Child 204 72.8 ± 32.8 74.7 ± 28.5 −1.9 −0.97 −5.8 2.0 .59 .49 .67
  School age 215 77.7 ± 30.2 70.4 ± 31.2 7.3 3.79 3.5 11.1 .56 .45 .65
  Adolescent 102 71.5 ± 30.0 65.3 ± 28.8 6.1 2.62 1.5 10.8 .67 .54 .76
 Nausea All Children 520 65.6 ± 28.3 69.4 ± 28.3 −3.7 −3.80 −5.5 −1.8 .70 .65 .74
  Young Child 203 61.8 ± 26.9 76.0 ± 24.7 −14.0 −10.04 − 16.8 − 11.3 .61 .28 .78
  School age 215 71.0 ± 28.6 67.3 ± 30.4 3.6 2.68 1.0 6.3 .77 .71 .82
  Adolescent 102 62.0 ± 29.1 60.4 ± 27.8 1.6 0.73 −2.7 5.9 .70 .59 .79
 Procedural anxiety All Children 520 63.9 ± 32.2 69.5 ± 30.0 −5.6 −4.99 −7.8 −3.4 .65 .59 .71
  Young Child 205 50.9 ± 30.7 64.1 ± 30.9 −13.2 −7.45 −16.7 −9.7 .61 .40 .73
  School age 214 69.5 ± 32.3 70.2 ± 30.4 −0.6 −0.37 − 4.0 2.7 .69 .61 .76
  Adolescent 101 78.4 ± 24.4 78.9 ± 24.3 − 0.6 −0.25 −5.2 4.1 .53 .38 .66
 Treatment anxiety All Children 509 86.3 ± 22.5 85.6 ± 21.3 0.6 0.65 −1.2 2.3 .58 .52 .64
  Young Child 199 82.6 ± 25.7 84.3 ± 22.4 −2.1 −1.39 −5.0 0.9 .62 .53 .70
  School age 212 87.6 ± 21.3 86.3 ± 20.6 1.3 0.98 −1.3 3.9 .58 .48 .66
  Adolescent 98 91.0 ± 16.4 86.8 ± 20.5 4.3 2.26 0.5 8.1 .48 .31 .61
 Worry All Children 515 65.6 ± 30.4 66.3 ± 31.7 −0.5 −0.33 −3.7 2.6 .32 .24 .40
  Young Child 200 64.8 ± 32.6 75.7 ± 29.7 −11.1 −4.12 −16.4 −5.8 .24 .10 .36
  School age 214 69.4 ± 28.0 64.6 ± 31.3 5.0 2.14 0.4 9.5 .34 .22 .45
  Adolescent 101 59.2 ± 30.0 51.0 ± 30.3 8.7 2.80 2.5 15.0 .44 .27 .58
 Cognitive problems All Children 508 75.6 ± 23.7 79.4 ±22.5 −3.9 −3.92 −5.8 −1.9 .53 .46 .59
  Young Child 199 74.1 ± 28.0 83.6 ± 19.7 −9.6 −6.04 −12.7 −6.5 .43 .26 .56
  School age 212 78.1 ± 26.3 78.5 ± 22.2 −0.5 −0.34 −3.1 2.2 .64 .55 .71
  Adolescent 96 73.3 ± 30.9 72.4 ± 24.7 0.5 0.20 −4.5 5.5 .50 .33 .63
 Perceived physical appearance All Children 488 73.1 ± 27.9 74.2 ± 27.6 −1.3 −0.98 −3.8 1.3 .48 .40 .54
  Young Child 203 71.1 ± 28.0 81.7 ± 23.1 −10.6 −5.70 − 14.3 −7.0 .43 .28 .55
  School age 197 75.8 ± 26.3 70.1 ± 29.6 6.0 3.28 2.4 9.7 .57 .46 .66
  Adolescent 88 71.6 ± 30.9 66.6 ± 28.4 4.0 1.13 −3.0 10.9 .41 .22 .57
 Communication All Children 483 63.4 ± 30.7 63.6 ± 29.0 −1.0 −0.78 −3.4 1.5 .58 .52 .64
  Young Child 197 55.8 ± 31.1 63.9 ± 29.2 −7.8 −4.08 −11.5 −4.0 .58 .48 .68
  School age 198 65.8 ± 29.2 60.7 ± 30.3 4.6 2.49 1.0 8.3 .61 .51 .69
  Adolescent 88 73.8 ± 29.6 69.7 ± 24.5 1.7 0.55 −4.3 7.7 .48 .30 .62
  1. Notes: Excluding missing values. Bold scores indicated significantly higher than another reports.
  2. aMean of the differences subtracting family proxy-reports from child self-reports, bComparing children self-reports and family proxy-reports using paired t-test
  3. Abbreviations: CI Confidence interval, ICC Intraclass correlation coefficient, PedsQL Pediatric Quality of Life Inventory™, SD Standard deviation