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Table 2 Descriptive statistics for HPA axis rhythmicity

From: Evidence for disruption of diurnal salivary cortisol rhythm in childhood obesity: relationships with anthropometry, puberty and physical activity

 

All (n = 57)

Obesity (n = 35)

Normal weight (n = 22)

P

Cortisol08:00(nmol/L)

6.23 (4.13,8.97)

5.79 (3.42,7.73)

8.44 (5.56,9.59)

0.030

Cortisol16:00 (nmol/L)

2.28 (1.77,3.32)

2.28 (1.72,3.18)

2.27 (1.91,3.52)

0.481

Cortisol23:00 (nmol/L)

0.59 (0.35,1.34)

1.10 (0.48,1.46)

0.40 (0.21,0.61)

< 0.001

AUC08:00–16:00 (nmol/L × h)

36.46 (25.35,48.15)

34.84 (23.01,45.99)

42.16 (32.12,52.04)

0.027

AUC16:00–23:00 (nmol/L × h)

11.73 (8.43,14.83)

11.90 (8.94,16.61)

11.51 (7.81,14.07)

0.263

AUC08:00–23:00 (nmol/L × h)

47.91 (36.31,61.56)

44.93 (34.66,60.94)

51.54 (42.75,66.87)

0.098

DCS (nmol/L/h)

−0.35(−0.54,-0.24)

−0.29(− 0.49,-0.14)

− 0.52(− 0.63,-0.34)

0.006

  1. Data are reported as the median (interquartile range), and the Mann–Whitney U-test was used. P: obesity group vs normal weight group