Table 1 Description of study patients by genotype, mean age, follow up time and percentage uptake of targeted interventions by early or late presentation to the Sickle Cell Unit in Jamaica (N = 290)
Early Intervention (N = 113) | Late Intervention (N = 177) | ||
|---|---|---|---|
SS | 110 (97%) | 168(95%) | |
Sβ0 | 3 (3%) | 7 (4%) | |
S0A | 0 | 2 (1%) | |
Mean Age at first visit, years(months) | 0.2 (2.9) | 2.3 (27.6) | t = 17.0; p < 0.010 |
Follow up time (years) | 5.2 | 3.2 | t= -17.0; p < 0.010 |
Proportion of patients diagnosed by newborn screening | 103 (92%) | 114 (64%) | χ2 = 90.6; p < 0.010 |
Proportion receiving Penicillin Prophylaxis | 111 (98%) | 134 (76%) | χ2 = 28.4; p < 0.010 |
Proportion receiving polyvalent pneumococcal vaccine | 106 (93%) | 156 (88%) | χ2 = 2.5; p = 0.111 |
Proportion with at least 2 doses PCV | 35 (31%) | 50 (28%) | χ2 = 0.2 ; p = 0.619 |