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Table 3 The changes of parameters about patients receiving invasive mechanical ventilation

From: A case series of children with adenovirus pneumonia: three-year experiences in a tertiary PICU

Variables D1 D3 D7
Survivor
(n = 56)
Nonsurvivor
(n = 11)
p-value Survivors
(n = 56)
Nonsurvivor
(n = 11)
P-value Survivor
(n = 56)
Nonsurvivor
(n = 11)
p-value
PIP,cmH2O 21 (19,23.5) 25 (21, 27) 0.145 21.5 (20, 24) 24 (20.5, 28) 0.377 22 (20, 26) 23 (21.75, 30) 0.27
MAP,cmH2O 11 (10, 12.5) 12 (10.5, 13.5) 0.372 11.5 (9.25, 13) 12 (11, 14.5) 0.412 12 (11.5, 14.5) 13 (11, 17.25) 0.458
PEEP, cm H2O 5 (4, 5) 5 (4, 5) 0.368 5 (5, 6) 5 (5, 5.5) 0.801 5 (5, 6) 6 (5, 6) 0.567
Cdyn, cm H2O/kg 0.4 (0.32, 0.48) 0.33 (0.31, 0.425) 0.286 0.52 (0.43, 0.55) 0.4 (0.31, 0.4) 0.012 0.5 (0.4, 0.56) 0.26 (0.22, 0.34) 0.045
Tidal volume, ml/kg 8 (7.8, 8) 7.2 (6.65, 8) 0.0029 8.3 (8, 8.5 8 (7.2, 8.1) 0.072 8.2 (8, 8.5) 7.55 (6.03, 8.35) 0.307
PaO2/FiO2ratio, mmHg 151 (113, 180.25) 140 (90, 143.5) 0.177 185 (139, 224) 111 (103,174.5) 0.038 170 (110, 212) 137.5 (89.5, 157.75) 0.384
Oxygenation index
PaCO2, mm Hg 44 (35, 50.25) 48 (41.5, 57.5) 0.138 45 (40.5, 48.5) 42 (37.5, 55.5) 0.727 44 (41, 48) 58 (43, 69.5) 0.305
PaO2, mm Hg 72 (57, 86.25) 73 (58.375, 84.5) 0.871 78 (72.5, 89.5) 78 (72.5, 89.5) 0.087 77 (55, 90) 65 (51.5, 75) 0.357
SaO2, % 95 (92, 96) 93 (90.5, 95) 0.265 96 (95, 97) 93 (91.5, 95.5) 0.008 96.5 (92.25, 98) 91 (89, 95.5) 0.655
  1. D1: initial day of invasive mechanical ventilation; D3: 3 days of ventilation; D7: 7 days of ventilation; PIP: Cdyn: lung dynamic compliance; MAP mean airway pressure