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Table 2 Clinical manifestations and laboratory results of Henoch–Schönlein purpura patients with and without gastrointestinal involvement

From: Fecal calprotectin as a marker of gastrointestinal involvement in pediatric Henoch–Schönlein purpura patients: a retrospective analysis

Variable Total HSP patients (n = 69) Gastrointestinal involvement (n = 40) Non-gastrointestinal involvement (n = 29) P value
Age (years) 6.85 ± 2.93 7.11 ± 2.67 6.48 ± 3.27 0.380
Male sex 37 (53.6%) 21 (52.5%) 16 (55.2%) 0.826
Duration of admission (days) 5.41 ± 5.27 7.25 ± 6.05 2.79 ± 1.97 0.000*
Joint symptoms 35 (50.7%) 16 (40.0%) 19 (65.5%) 0.036*
Kidney involvement 16 (23.2%) 10 (25.0%) 6 (20.7%) 0.675
HSP clinical score 1.99 ± 1.53 2.65 ± 1.59 1.07 ± 0.80 0.000*
HSP recurrence 23 (33.3%) 15 (37.5%) 8 (27.6%) 0.389
Gastrointestinal symptom recurrence 19 (27.5%) 12 (30.0%) 7 (24.1%) 0.591
Positive stool occult blood result 17 (24.6%) 17 (42.5%) 0 (0%) 0.000*
Fecal calprotectin (mg/kg) 252.7 ± 343.8 379.9 ± 399.8 77.4 ± 97.6 0.000*
WBC count (106/L) 11,757 ± 5133 12,365 ± 6015 10,889 ± 3434 0.246
ANC (μL) 7673 ± 4388 8476 ± 4716 6526 ± 3652 0.071
ESR (mm/h) 23.74 ± 12.46 25.50 ± 12.62 21.04 ± 11.95 0.157
C-reactive protein (mg/L) 5.87 ± 6.39 5.18 ± 5.65 6.87 ± 7.31 0.285
FDP (μg/mL) (n = 57) 9.14 ± 9.16 11.08 ± 11.14 6.73 ± 5.07 0.064
D-dimer (μg/mL) (n = 57) 2.34 ± 2.45 2.93 ± 2.89 1.61 ± 1.50 0.036*
  1. HSP Henoch–Schönlein purpura, WBC White blood cell, ANC Absolute neutrophil count, ESR Erythrocyte sedimentation rate, FDP Fibrin degradation product
  2. *Significant findings at P < 0.05