Table 3 Comparison of Dubin Johnson syndrome and other causes of neonatal cholestasis
From: Mutation spectrum and biochemical features in infants with neonatal Dubin-Johnson syndrome
|  | Dubin Johnson syndrome (n = 06) | Other causes (n = 129) | p value |
|---|---|---|---|
Male : Female | 2 : 4 | 75 : 54 | 0.232 |
Term baby | 6 | 98 | 0.173 |
Growth failure | 0 | 21 | 0.284 |
Jaundice | 6 | 81 | 0.125 |
Hepatomegaly | 0 | 37 | 0.161 |
Splenomegaly | 0 | 20 | 0.342 |
Acholic stool | 2 | 46 | 0.908 |
DB (mg/dL) | 7.4 (3.7–11.0) | 4.7 (0.8–15.7) | 0.036 |
TB (mg/dL) | 11.5 (5.8–15.6) | 7.6 (1.3–29.4) | 0.026 |
Cholesterol (mg/dL) | 166 (123–246) | 154 (23–391) | 0.467 |
AST (IU/L) | 27 (25–61) | 225 (17-3801) | 0.002 |
ALT (IU/L) | 15 (11–40) | 143 (3-2493) | 0.007 |
GGT (IU/L) | 149 (33–209) | 290 (11-1605) | 0.265 |
PT (INR) | 1.10 (0.91–1.11) | 1.21 (0.77–3.28) | 0.255 |