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Table 1 Identified causes of neonatal cholestasis in our cohort

From: Mutation spectrum and biochemical features in infants with neonatal Dubin-Johnson syndrome

Diagnosis

N = 135

Biliary atresia

37 (27.4%)

Choledochal cyst

11 (8.1%)

NICCD

7 (5.2%)

Dubin Johnson syndrome

6 (4.5%)

TPN induced cholestasis

6 (4.5%)

Alagille syndrome

4 (3.0%)

Neonatal hemochromatosis

2 (1.5%)

ARC syndrome

2 (1.5%)

Congenital portosystemic shunt

2 (1.5%)

PFIC

1 (0.7%)

Galactosemia

1 (0.7%)

HSV

1 (0.7%)

CMV

1 (0.7%)

Sepsis

1 (0.7%)

Idiopathic neonatal cholestasis

53 (39.3%)

  1. NICCD Neonatal intrahepatic cholestasis caused by citrin deficiency; TPN Total parenteral nutrition; ARC Arthrogryposis-renal dysfunction-cholestasis; PFIC Progressive familial intrahepatic cholestasis; HSV Herpes Simplex Virus; CMV Cytomegalovirus