Fig. 3

Clinical course of blood gas analysis evaluation and cases of pulmonary function tests measured at our institute. a. In both case 1 and case 2, the AaDO₂ remained high from birth until the change to CMV. After changing to CMV, AaDO₂ decreased significantly in both cases. b. The PaO₂/FiO₂ ratio remained below 100 before changing to CMV but improved after the change to CMV. c. In case 1, the OI decreased 24 h after birth, but increased before switching to CMV. The OI declined after the change to CMV. In case 2, the OI gradually increased after birth, and rose to a level that required consideration of ECMO before the pulmonary function test. After switching to CMV, the OI dropped prominently. d. The values of Crs and Rrs measured at our institute. Black dots are death cases and red dots are the cases described in this article using HFOV as the initial ventilation. Blue dots are the cases whose lives were saved using HFOV as the initial ventilation, which was not changed to CMV. Green dots are the cases in whom initial ventilation was CMV, which was not changed to HFOV. The triangle points are cases with chromosomal abnormalities, and dots are the cases without chromosomal abnormalities. CMV: conventional mechanical ventilation. ECMO: extra-corporeal membrane oxygenation. Crs: respiratory-system compliance. Rrs: respiratory-system resistance. HFOV: high frequency oscillatory ventilation