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Table 2 Clinical characteristics of the study population

From: Factors affecting bone maturation in Chinese girls aged 4–8 years with isolated premature thelarche

 

Advanced BA group

Control group

p-value

Basic LH (IU/L)

0.24 (0.15, 0.42)

0.24 (0.13, 0.44)

0.902

Peak LH (IU/L)

3.49 (2.52, 4.18)

3.57 (2.80, 4.16)

0.301

Peak LH/peak FSH

0.22 (0.17, 0.29)

0.21 (0.16, 0.29)

0.316

DHEAS (µg/dL)

42.85 (23.78, 60.83)

29.50 (16.80, 52.40)

< 0.001

DHEAS SDS

1.94 (0.46, 4.15)

0.85 (-0.14, 2.47)

< 0.001

Androsterone (ng/mL)

0.30 (0.15, 0.48)

0.15 (0.15, 0.35)

< 0.001

Insulin (µIU/mL)

6.68 (5.08, 9.37)

5.50 (3.56, 8.10)

< 0.001

SHBG (nmol/L)

58.15 (41.75, 75.23)

71.70 (52.80, 89.90)

< 0.001

IGF-1 (ng/mL)

238.00 (190.00, 300.25)

204.00 (168.00, 241.00)

< 0.001

IGF-1 SDS

0.44 (-0.30, 1.29)

-0.27 (-0.73, 0.48)

< 0.001

Oestradiol (pmol/L)

10.00 (10.00, 20.00)

10.00 (10.00, 10.00)

0.257

Triglyceride (mmol/L)

0.80 (0.61, 1.04)

0.85 (0.63, 1.05)

0.366

Total cholesterol (mmol/L)

3.76 (3.37, 4.35)

3.86 (3.49, 4.34)

0.299

HDL (mmol/L)

1.23 (1.06, 1.38)

1.23 (1.05, 1.42)

0.646

LDL (mmol/L)

2.27 (1.96, 2.63)

2.36 (2.07, 2.69)

0.215

Uterine length (cm)

3.41(3.08,3.67)

3.27(2.93,3.49)

0.009

Ovarian volume (ml)

1.23(0.82,1.74)

1.13(0.78,1.76)

0.389

  1. Data presented as the median and quartiles
  2. BA Bone age, LH Luteinizing hormone, FSH Follicle-stimulating hormone, DHEAS Dehydroepiandrosterone sulfate, SDS Standard deviation score, SHBG Sex hormone binding globulin, IGF-1 Insulin-like growth factor-1, HDL High-density lipoprotein, LDL Low-density lipoprotein