Skip to main content

Table 2 Clinical characteristics of the study population

From: Factors affecting bone maturation in Chinese girls aged 4–8 years with isolated premature thelarche

  Advanced BA group Control group p-value
Basic LH (IU/L) 0.24 (0.15, 0.42) 0.24 (0.13, 0.44) 0.902
Peak LH (IU/L) 3.49 (2.52, 4.18) 3.57 (2.80, 4.16) 0.301
Peak LH/peak FSH 0.22 (0.17, 0.29) 0.21 (0.16, 0.29) 0.316
DHEAS (µg/dL) 42.85 (23.78, 60.83) 29.50 (16.80, 52.40) < 0.001
DHEAS SDS 1.94 (0.46, 4.15) 0.85 (-0.14, 2.47) < 0.001
Androsterone (ng/mL) 0.30 (0.15, 0.48) 0.15 (0.15, 0.35) < 0.001
Insulin (µIU/mL) 6.68 (5.08, 9.37) 5.50 (3.56, 8.10) < 0.001
SHBG (nmol/L) 58.15 (41.75, 75.23) 71.70 (52.80, 89.90) < 0.001
IGF-1 (ng/mL) 238.00 (190.00, 300.25) 204.00 (168.00, 241.00) < 0.001
IGF-1 SDS 0.44 (-0.30, 1.29) -0.27 (-0.73, 0.48) < 0.001
Oestradiol (pmol/L) 10.00 (10.00, 20.00) 10.00 (10.00, 10.00) 0.257
Triglyceride (mmol/L) 0.80 (0.61, 1.04) 0.85 (0.63, 1.05) 0.366
Total cholesterol (mmol/L) 3.76 (3.37, 4.35) 3.86 (3.49, 4.34) 0.299
HDL (mmol/L) 1.23 (1.06, 1.38) 1.23 (1.05, 1.42) 0.646
LDL (mmol/L) 2.27 (1.96, 2.63) 2.36 (2.07, 2.69) 0.215
Uterine length (cm) 3.41(3.08,3.67) 3.27(2.93,3.49) 0.009
Ovarian volume (ml) 1.23(0.82,1.74) 1.13(0.78,1.76) 0.389
  1. Data presented as the median and quartiles
  2. BA Bone age, LH Luteinizing hormone, FSH Follicle-stimulating hormone, DHEAS Dehydroepiandrosterone sulfate, SDS Standard deviation score, SHBG Sex hormone binding globulin, IGF-1 Insulin-like growth factor-1, HDL High-density lipoprotein, LDL Low-density lipoprotein