Fig. 5

E2F1 is regulated by MYCN amplification and associated with the prognosis of neuroblastoma. a Enrichment plots of transcription factor E2F1 in GSE19274 and GSE85047 datasets. b Box plots showed the relative E2F1 expression levels in neuroblastoma patients with (red) or without (green) MYCN amplification in TARGET, GSE19274, GSE73517, GSE49710 and GSE85047 datasets. P values were performed using Student’s t test. c The Kaplan-Meier plots demonstrated the prognostic effects of E2F1 in patients with neuroblastoma in TARGET and GSE85047 datasets