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Table 4 Echocardiographic outcomes of newborns with cardiac murmur (N = 1928)a

From: Congenital heart disease diagnosed with echocardiogram in newborns with asymptomatic cardiac murmurs: a systematic review

Echocardiographic outcomes n (%) References
Shunt lesions Ventricular septal defect 282 (14.6) [24, 26, 28,29,30,31,32,33,34]
Atrial septal defect (≥ 4 mm) 55 (2.8) [24, 28,29,30,31,32,33]
Ventricular septal defect + Atrial septal defect 15 (0.8) [29, 31, 33]
Atrioventricular septal defect 4 (0.2) [24, 26, 32, 34]
Significant patent ductus arteriosus 50 (2.6) [24, 30, 34]
Right side heart lesions Pulmonary valve anomaly (dysplasia, stenosis) 37 (1.9) [24, 26, 28,29,30,31,32,33,34]
Tetralogy of Fallot 15 (0.8) [26, 28,29,30, 32,33,34]
Ebstein anomaly 2 (0.1) [29, 34]
Left side heart lesions Cor triatriatum 1 (0.1) [29]
Mitral valve regurgitation 4 (0.2) [29, 32]
Aortic valve anomaly (bicuspid valve, stenosis) 18 (0.9) [24, 28,29,30, 33, 34, 36]
Hypoplastic left heart syndrome 3 (0.2) [29, 33]
Coarctation of the aorta 9 (0.5) [28,29,30, 32, 34]
Connection lesions Transposition of great arteries 6 (0.3) [24, 29, 31]
Partial anomalous pulmonary venous return 4 (0.2) [26, 30, 34]
Anomalous origin of the right pulmonary artery from the ascending aorta 1 (0.1) [29]
Others Coronary artery fistula 1 (0.1) [35]
Ventricular hypertrophy 5 (0.3) [31]
Normal or physiologic variant 1211 (62.8) [24,25,26, 28,29,30,31,32,33,34]
Not described 343 (17.8) [24, 25, 32, 34]
  1. aThe number of diagnoses exceeds the number of patients with congenital heart disease because some patients had multiple diagnoses