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Table 1 Characteristics of the studies included in the final analysis

From: Congenital heart disease diagnosed with echocardiogram in newborns with asymptomatic cardiac murmurs: a systematic review

Sources

Country

Study design

Study period

Clinical settings

Participants (n)

Sex (M/F)

Mean age (days)

Ainsworth et al. 1999, [28]

United Kingdom (Newcastle upon Tyne)

Prospective cohort study

Jan. 1995–Dec. 1996

Nursery

46

NP

NP

Rein et al. 2000, [29]

Israel (Jerusalem)

Retrospective cohort study

Jan. 1994–Dec. 1996

Nursery

170

85:85

NP

Azhar et al. 2006, [24]

Canada (Ontario/Ottawa)

Prospective cross-sectional study

Jul. 1997–Jun. 1998

NICU

75

NP

NP

Mackie et al. 2009, [30]

Canada (Quebec/ Montreal)

Prospective cross-sectional study

Oct. 2004–Jul. 2006

Outpatient

201

95:106

12

Gokmen et al. 2009, [25]

Turkey (Konya)

Prospective cross-sectional study

NP

6 months

Nursery

53

NP

NP

Mirzarahimi et al. 2011, [31]

Iran (Ardabil)

Cross-sectional study

Sept. 2006–Sept. 2007

Nursery

NICU

91

NP

NP

Singh et al. 2012, [32]

United Kingdom (Birmingham)

Retrospective cohort study

Jan. 2008–Dec. 2010

Nursery

205

NP

2

Al-Ammouri et al. 2016, [33]

Jordan (Amman)

Retrospective cohort study

Aug. 2007–Jun. 2014

Nursery

309

167:142

NP

Minocha et al. 2018, [26]

United States (Florida/Miami)

Retrospective cohort study

Jan. 2013–Dec. 2016

Nursery

422

NP

NP

Fenster et al. 2018, [34]

United States (Wisconsin/Madison)

Retrospective cohort study

Jan. 2008–Dec. 2015

Nursery

354

NP

2

Ceresnak et al. 2007, [35]

United States (New York)

Case report

NP

Nursery

1

1 male

2

Paech et al. 2013, [36]

Germany (Leipzig)

Case report

NP

NICU

1

NP

NP

  1. Abbreviations: NP, not provided; NICU, neonatal intensive care unit; M, male; F, female