Table 4 Comparison of xTAG GPP with the routine tests and the results of XTAG GPP for the detection of enteric pathogens from patients with persistent and chronic diarrhea
Class | Target | GPP | No. of samples by routine tests | Performance of the xTAG GPP assay | ||
|---|---|---|---|---|---|---|
+ | – | Sensitivity | %Specificity | |||
Virus | Adenovirus 40/41 | + | 0 | 0 | ||
– | 0 | 199 | 0 | 100(199/199) | ||
Rotavirus A | + | 63 | 6 | |||
– | 2 | 50 | 96.9(63/65) | 89.3(50/52) | ||
Norovirus GI/GII | + | 22 | 19 | |||
– | 0 | 158 | 100(22/22) | 89.3(158/177) | ||
Bacteria | Salmonella | + | 2 | 15 | ||
– | 4 | 182 | 33.3(2/6) | 92.3(182/197) | ||
Campylobacter | + | 43 | 0 | |||
– | 0 | 199 | 100(43/43) | 100(199/199) | ||
Shigella | + | 1 | 3 | |||
– | 0 | 195 | 100 (1/1) | 98.5(195/198) | ||
ClostridiumdifficileToxin A/B | + | 27 | 3 | |||
– | 0 | 169 | 100(27/27) | 84.9(169/172) | ||
ETEC | + | 0 | 0 | |||
– | 0 | 199 | 0 | 100(199/199) | ||
EscherichiacoliO157 | + | 0 | 2 | |||
– | 0 | 197 | 0 | 99.0(192/199) | ||
STEC | + | 0 | 0 | |||
– | 0 | 199 | 0 | 100(199/199) | ||
Yersinia enterocolitica | + | 0 | 0 | |||
– | 0 | 199 | 0 | 100(199/199) | ||
Vibrio cholerae | + | 0 | 0 | |||
– | 0 | 199 | 0 | 100(199/199) | ||
Parasite | Giardia | + | 0 | 0 | ||
– | 0 | 199 | 0 | 100(199/199) | ||
Entamoeba histolytica | + | 0 | 1 | |||
– | 0 | 198 | 0 | 99.5(198/199) | ||
Cryptosporidium | + | 0 | 2 | |||
– | 0 | 197 | 0 | 99.0(197/199) | ||
+ | 158 | 51 | ||||
Total | – | 6 | 2739 | 96.3(158/166) | 98.2(2739/2790) | |