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Table 4 Comparison of xTAG GPP with the routine tests and the results of XTAG GPP for the detection of enteric pathogens from patients with persistent and chronic diarrhea

From: The application research of xTAG GPP multiplex PCR in the diagnosis of persistent and chronic diarrhea in children

Class Target GPP No. of samples by routine tests Performance of the xTAG GPP assay
+ Sensitivity %Specificity
Virus Adenovirus 40/41 + 0 0   
0 199 0 100(199/199)
Rotavirus A + 63 6   
2 50 96.9(63/65) 89.3(50/52)
Norovirus GI/GII + 22 19   
0 158 100(22/22) 89.3(158/177)
Bacteria Salmonella + 2 15   
4 182 33.3(2/6) 92.3(182/197)
Campylobacter + 43 0   
0 199 100(43/43) 100(199/199)
Shigella + 1 3   
0 195 100 (1/1) 98.5(195/198)
ClostridiumdifficileToxin A/B + 27 3   
0 169 100(27/27) 84.9(169/172)
ETEC + 0 0   
0 199 0 100(199/199)
EscherichiacoliO157 + 0 2   
0 197 0 99.0(192/199)
STEC + 0 0   
0 199 0 100(199/199)
Yersinia enterocolitica + 0 0   
0 199 0 100(199/199)
Vibrio cholerae + 0 0   
0 199 0 100(199/199)
Parasite Giardia + 0 0   
0 199 0 100(199/199)
Entamoeba histolytica + 0 1   
0 198 0 99.5(198/199)
Cryptosporidium + 0 2   
0 197 0 99.0(197/199)
+ 158 51   
Total 6 2739 96.3(158/166) 98.2(2739/2790)