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Table 4 SNP associated with the hemolytic subphenotype

From: High fetal hemoglobin level is associated with increased risk of cerebral vasculopathy in children with sickle cell disease in Mayotte

SNP

Avantageous allele/Disadvantageous allele

Allele frequency (%)

OR (95%CI)

P

BCL11A rs4671393

A/G

37%

3,13 [1,1-8,89]

0,047

BCL11A rs11886868

C/T

43%

4,28 [1,6-11,5]

0,005

BCL11A rs1427407

T/G

15%

4,02 [1,75-9,22]

0,001

HMIP rs9399137

C/T

7%

5,92 [1,28-27,4]

0,012

Xmn1 rs7842144

T/C

6%

0,76

BCL11A rs10189857

A/G

54%

0,85

HMIP rs28384513

C/A

67%

1

HMIP rs66650371

Deletion/ACT

37%

0,39