Table 3 Comparison of patients characteristics according to the alpha thalassemia trait
Alpha thalassemia trait (n = 80) | No alpha thalassemia trait (n = 52) | P | |
|---|---|---|---|
Mean (±SD) or n (%) | |||
Hb (g/d L) | 8,2 (±0,1) | 7,7 (±0,2) | 0,007 |
Hématocrit (%) | 25,6 (±0,4) | 23,8 (±0,5) | 0,004 |
MCV (fL) | 73,3 (±1) | 81,8 (±1,5) | < 0,001 |
Reticulocytes (G/L) | 239,6 (±10) | 288,2 (±13,8) | 0,004 |
TCD | 0,017 | ||
Normal | 72 (90) | 37 (71,2) | |
Limit | 3 (3,7) | 8 (15,4) | |
Pathological | 5 (6,3) | 7 (13,4) | |
Splenomegaly ratio | 0,54 (±0,03) | 0,43 (±0,05) | 0,057 |
Cerebral vasculopathy | 0,004 | ||
Yes | 78 (91,8) | 43 (72,9) | |
Pathological TCD/MRI | 7 (8,2) | 13 (22) | |
Stroke | 0 | 3 (5,1) | |
RBC Transfusion | 0,028 | ||
No | 28 (29,4) | 10 (15,6) | |
Occasionnally | 60 (63,2) | 42 (65,6) | |
Exchange transfusion | 7 (7,4) | 12 (18,8) | |