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Table 1 Comparison of patients characteristics according to the sickle genotypes

From: High fetal hemoglobin level is associated with increased risk of cerebral vasculopathy in children with sickle cell disease in Mayotte

 SS (n = 118)Sbeta° (n = 26)Sbeta+ (n = 19)P
Mean (±SD) or n (%)
Hb (g/dL)7,8 (±0,1)8,3 (±0,3)8,8 (±0,1) 
Hematocrit (%)24,1 (±0,3)27,0 (±0,7)28,3 (±1,0) 
MCV (fL)80,3 (±0,9)65,8 (±1,3)69,3 (±2,2) 
MCHC (g/dL)32,7 (±0,1)31,0 (±0,3)31,7 (±0,3) 
Reticulocytes (G/L)268,1 (±9,8)250,0 (±20,9)179,1 (±19,0)0,003
Leukocytes (G/L)13,2 (±0,4)10,6 (±0,7)11,0 (±0,7)0,007
Hospitalization/year   0,003
No13 (11,1)8 (32)7 (38,9) 
1 to 291 (77,8)17 (68)11 (61,1) 
≥ 313 (11,1)00 
Red Blood Cell Transfusion érythrocytaire   0,001
Never20 (17,1)13 (52)8 (42,1) 
Occasionnally78 (66,7)11 (44)11 (57,9) 
Transfusion therapy19 (16,2)1 (4)0 
Infection61 (55)8 (30,8)6 (31,6)0,026
Acute Chest Syndrome27 (23,9)04 (21,1)0,009
Number of ACS/year   0,041
Never80 (74,1)25 (100)15 (78,9) 
122 (20,4)03 (15,8) 
≥ 26 (5,5)01 (5,3) 
Cholelithiasis28 (26,4)4 (18,2)00,038