Table 1 Comparison of patients characteristics according to the sickle genotypes
SS (n = 118) | Sbeta° (n = 26) | Sbeta+ (n = 19) | P | |
|---|---|---|---|---|
Mean (±SD) or n (%) | ||||
Hb (g/dL) | 7,8 (±0,1) | 8,3 (±0,3) | 8,8 (±0,1) | |
Hematocrit (%) | 24,1 (±0,3) | 27,0 (±0,7) | 28,3 (±1,0) | |
MCV (fL) | 80,3 (±0,9) | 65,8 (±1,3) | 69,3 (±2,2) | |
MCHC (g/dL) | 32,7 (±0,1) | 31,0 (±0,3) | 31,7 (±0,3) | |
Reticulocytes (G/L) | 268,1 (±9,8) | 250,0 (±20,9) | 179,1 (±19,0) | 0,003 |
Leukocytes (G/L) | 13,2 (±0,4) | 10,6 (±0,7) | 11,0 (±0,7) | 0,007 |
Hospitalization/year | 0,003 | |||
No | 13 (11,1) | 8 (32) | 7 (38,9) | |
1 to 2 | 91 (77,8) | 17 (68) | 11 (61,1) | |
≥ 3 | 13 (11,1) | 0 | 0 | |
Red Blood Cell Transfusion érythrocytaire | 0,001 | |||
Never | 20 (17,1) | 13 (52) | 8 (42,1) | |
Occasionnally | 78 (66,7) | 11 (44) | 11 (57,9) | |
Transfusion therapy | 19 (16,2) | 1 (4) | 0 | |
Infection | 61 (55) | 8 (30,8) | 6 (31,6) | 0,026 |
Acute Chest Syndrome | 27 (23,9) | 0 | 4 (21,1) | 0,009 |
Number of ACS/year | 0,041 | |||
Never | 80 (74,1) | 25 (100) | 15 (78,9) | |
1 | 22 (20,4) | 0 | 3 (15,8) | |
≥ 2 | 6 (5,5) | 0 | 1 (5,3) | |
Cholelithiasis | 28 (26,4) | 4 (18,2) | 0 | 0,038 |