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Table 4 The parallel test results for GGT and LSM in BA infants

From: Combination of gamma-glutamyl transferase and liver stiffness measurement for biliary atresia screening at different ages: a retrospective analysis of 282 infants

  AUCYouden index95% CIsensitivityspecificityPPVNPV
All patientsGGT > 192.5 U/L or LSM > 9.5 kPa0.7850.5700.730–0.8400.9780.5920.6810.945
Group A (≤60d)GGT > 191.2 U/L or LSM > 7.5 kPa0.7460.4930.651–0.8420.9730.5200.7350.923
Group B (61-90d)GGT > 213.2 U/L or LSM > 10.0 kPa0.7840.5670.703–0.8650.9810.5860.6540.976
Group C (91-120d)GGT > 281.5 U/L or LSM > 11.0 kPa0.8700.7410.753–0.9881.0000.7410.5831.000
  1. CI Confidence interval, PPV Positive predictive value, NPV Negative predictive value, LSM Liver stiffness measurement, GGT Gamma-glutamyl transferase, AUC The area under the receiver operating characteristic curve