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Table 4 Clinical characteristics of all patients and patients of different groups

From: Radiation therapy is an important factor to improve survival in pediatric patients with head and neck rhabdomyosarcoma by enhancing local control: a historical cohort study from a single center

 All patients
n (%)
All patientsPatients with events
IRT
n
NIRT
n
pSRT
n
NSRT
n
p
Total cases56 (100%)34221511
Gender
 Male31 (55.4%)229 65 
 Female25 (44.6%)12130.080961.000#
Age at diagnosis
  ≤ 1 y or ≥ 10 ys17 (30.4%)107 44 
 >1–9 ys39 (69.6%)24150.8481170.683#
Site of origin
 Orbit22 (39.3%)148 91 
 Parameningeal32 (57.1%)1913 410 
 Other head & neck2 (3.6%)110.813*200.002*#
Tumor size
  ≤ 5 cm37 (66.1%)2512 114 
 >5 cm19 (33.9%)9100.143470.109#
Histologic subtype
 Embryonal27 (48.2%)1611 65 
 Alveolar29 (51.8%)18110.830961.000#
Primary tumor invasiveness
 T120 (35.7%)128 72 
 T236 (64.3%)22140.935890.217#
Regional nodal involvement
 N030 (53.6%)219 94 
 N126 (46.4%)13120.126670.428#
Metastasis
 M049 (87.5%)3217 139 
 M17 (12.5%)250.099#221.000#
TNM pretreatment stage
 Stage 124 (42.9%)159 111 
 Stage 27 (12.5%)52 02 
 Stage 318 (32.1%)126 26 
 Stage 47 (12.5%)25NA22NA
Surgical-pathologic group
 Group I0 (0%)00 00 
 Group II8 (14.3%)53 30 
 Group III41 (73.2%)2714 109 
 Group IV7 (12.5%)25NA22NA
Risk group
 Low risk11 (19.6%)65 51 
 Intermediate risk38 (67.9%)2612 88 
 High risk7 (12.5%)25NA22NA
  1. IRT: initial RT; NIRT: non-initial RT; SRT: salvage RT; NSRT: non-salvage RT.
  2. *: Tested between parameningeal and nonparameningeal (orbit+other head & neck) groups
  3. #: Fisher’s exact test
  4. NA: not tested because of limited sample size