Skip to main content

Table 4 Clinical characteristics of all patients and patients of different groups

From: Radiation therapy is an important factor to improve survival in pediatric patients with head and neck rhabdomyosarcoma by enhancing local control: a historical cohort study from a single center

 

All patients

n (%)

All patients

Patients with events

IRT

n

NIRT

n

p

SRT

n

NSRT

n

p

Total cases

56 (100%)

34

22

–

15

11

–

Gender

 Male

31 (55.4%)

22

9

 

6

5

 

 Female

25 (44.6%)

12

13

0.080

9

6

1.000#

Age at diagnosis

  ≤ 1 y or ≥ 10 ys

17 (30.4%)

10

7

 

4

4

 

 >1–9 ys

39 (69.6%)

24

15

0.848

11

7

0.683#

Site of origin

 Orbit

22 (39.3%)

14

8

 

9

1

 

 Parameningeal

32 (57.1%)

19

13

 

4

10

 

 Other head & neck

2 (3.6%)

1

1

0.813*

2

0

0.002*#

Tumor size

  ≤ 5 cm

37 (66.1%)

25

12

 

11

4

 

 >5 cm

19 (33.9%)

9

10

0.143

4

7

0.109#

Histologic subtype

 Embryonal

27 (48.2%)

16

11

 

6

5

 

 Alveolar

29 (51.8%)

18

11

0.830

9

6

1.000#

Primary tumor invasiveness

 T1

20 (35.7%)

12

8

 

7

2

 

 T2

36 (64.3%)

22

14

0.935

8

9

0.217#

Regional nodal involvement

 N0

30 (53.6%)

21

9

 

9

4

 

 N1

26 (46.4%)

13

12

0.126

6

7

0.428#

Metastasis

 M0

49 (87.5%)

32

17

 

13

9

 

 M1

7 (12.5%)

2

5

0.099#

2

2

1.000#

TNM pretreatment stage

 Stage 1

24 (42.9%)

15

9

 

11

1

 

 Stage 2

7 (12.5%)

5

2

 

0

2

 

 Stage 3

18 (32.1%)

12

6

 

2

6

 

 Stage 4

7 (12.5%)

2

5

NA

2

2

NA

Surgical-pathologic group

 Group I

0 (0%)

0

0

 

0

0

 

 Group II

8 (14.3%)

5

3

 

3

0

 

 Group III

41 (73.2%)

27

14

 

10

9

 

 Group IV

7 (12.5%)

2

5

NA

2

2

NA

Risk group

 Low risk

11 (19.6%)

6

5

 

5

1

 

 Intermediate risk

38 (67.9%)

26

12

 

8

8

 

 High risk

7 (12.5%)

2

5

NA

2

2

NA

  1. IRT: initial RT; NIRT: non-initial RT; SRT: salvage RT; NSRT: non-salvage RT.
  2. *: Tested between parameningeal and nonparameningeal (orbit+other head & neck) groups
  3. #: Fisher’s exact test
  4. NA: not tested because of limited sample size