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Table 2 IRS surgical-pathologic group system

From: Radiation therapy is an important factor to improve survival in pediatric patients with head and neck rhabdomyosarcoma by enhancing local control: a historical cohort study from a single center

Group

Definition

I

Localized disease, completely resected

II

Total gross resection, with evidence of regional spread

 A

Grossly resected tumor with microscopic residual disease

 B

Involved regional nodes completely resected with no microscopic residual disease

 C

Involved regional nodes grossly resected with evidence of microscopic residual disease

III

Biopsy only or incomplete resection with gross residual disease

IV

Distant metastatic disease (excludes regional nodes and adjacent organ infiltration)