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Table 2 IRS surgical-pathologic group system

From: Radiation therapy is an important factor to improve survival in pediatric patients with head and neck rhabdomyosarcoma by enhancing local control: a historical cohort study from a single center

GroupDefinition
ILocalized disease, completely resected
IITotal gross resection, with evidence of regional spread
 AGrossly resected tumor with microscopic residual disease
 BInvolved regional nodes completely resected with no microscopic residual disease
 CInvolved regional nodes grossly resected with evidence of microscopic residual disease
IIIBiopsy only or incomplete resection with gross residual disease
IVDistant metastatic disease (excludes regional nodes and adjacent organ infiltration)