Table 6 Tacrolimus pharmacokinetic data and occurrence of acute rejection (AR) in the 49 patients of the study
| Â | Days | No AR (41 patients) | AR (8 patients) |
|---|---|---|---|
Dose/kg (mg/kg) | day 7 | 0.17 ± 0.08 | 0.13 ± 0.03 |
day 30 | 0.15 ± 0.08 | 0.15 ± 0.06 | |
day 90 | 0.11 ± 0.08 | 0.11 ± 0.08 | |
day 80 | 0.09 ± 0.07 | 0.10 ± 0.04 | |
day 360 | 0.07 ± 0.06 | 0.08 ± 0.04 | |
C0/(dose/kg) (ng/ml)/(mg/kg) | day 7 | 78.07 ± 45.55 | 100.51 ± 89.31 |
day 30 | 115.22 ± 86.70 | 72.48 ± 42.91 | |
day 90 | 115.37 ± 97.21 | 91.56 ± 49.57 | |
day 180 | 130.45 ± 102.76 | 90.36 ± 64.71 | |
day 360 | 190.11 ± 196.61 | 98.31 ± 51.3 |