Table 1 Baseline characteristics of included infants, timing of surfactant doses, collection of samples and microbiological findings
No. | Gestational age at birth in weeks | Weight at birth in gram | Time of surfactant administration after birth in hours: minutes *cultured sample; *e collected, but excluded; -- missed | Microbiological findings Bacterium (Colony Forming Units (CFU)) | ||
|---|---|---|---|---|---|---|
1st dose | 2nd dose | 3rd dose | ||||
1 | 24 + 5/7 | 345 | 00:13 -- | 09:09 * | – | viridans group streptococci (160 CFU) |
2 | 33 + 2/7 | 1730 | 34:23 * | – | – | – |
3 | 29 + 0/7 | 1190 | 05:30 * | – | – | – |
4 | 29 + 6/7 | 1600 | 00:22 -- | 17:22 * | – | – |
5 | 25 + 0/7 | 660 | 02:10 *e | 17:50 * | – | – |
6 | 27 + 2/7 | 980 | 01:02 * | – | – | – |
7 | 31 + 4/7 | 2145 | 00:12 * | – | – | – |
8 | 28 + 6/7 | 1340 | 01:49 * | – | – | – |
9 | 31 + 2/7 | 1490 | 00:20 -- | 02:38 * | 18:53 -- | – |
10 | 33 + 1/7 | 1990 | 25:21 * | – | – | viridans group streptococci (160 CFU) coagulase-negative staphylococci (90 CFU) |
11 | 30 + 0/7 | 980 | 33:58 * | – | – | coagulase-negative staphylococci (30 CFU) |
12 | 30 + 2/7 | 1220 | 00:08 * | – | – | – |
13 | 26 + 6/7 | 655 | 26:21 * | – | – | – |
14 | 25 + 4/7 | 495 | 02:24 * | 37:09 -- | – | – |
15 | 25 + 2/7 | 685 | 00:43 * | – | – | Staphylococcus aureus(60 CFU) |
16 | 29 + 5/7 | 1380 | 02:56 * | – | – | – |
17 | 24 + 6/7 | 880 | 01:14 * | 16:12 *e | – | – |
18 | 25 + 4/7 | 555 | 01:03 -- | 14:20 * | – | – |
19 | 27 + 1/7 | 585 | 00:27 * | – | – | – |
20 | 30 + 0/7 | 780 | 14:21 -- | 17:55 *e | 21:40 * | – |