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Table 1 Definitions of cohort measurement parameters

From: Psychosocial, behavioral and clinical correlates of children with overweight and obesity

 DescriptionReference
Weight categoriesAge < 18 yearsAge ≥ 18 years 
 OverweightBMI 85-95th percentileBMI 25–30 kg/m2CDC 2000 growth curves; Gulati 2012; Skinner 2015; Skinner 2016
 Class 1 obesityBMI 95–120% of 95th percentileBMI 30–35 kg/m2
 Class 2 obesityBMI 120–140% of 95th percentileBMI 35–40 kg/m2
 Class 3 obesityBMI > 140% of 95th percentileBMI > 40 kg/m2
Laboratory parametersDefinition of Abnormal  
 Fasting blood glucose≥ 126 mg/dLAll agesADA diabetes care guidelines 2018
 Fasting insulin> 12 uIU/mLAll agesLaboratory reference range
 HOMA-IR≥ 3 unitsAll ages 
 C-reactive protein≥ 3 mg/dLAll agesFramingham Heart Study CHD Risk Scores; Jialal 2004; Buckley 2009
 LDL≥110 mg/dL≥120 mg/dLNHLBI Integrated Guidelines for Cardiovascular Risk Reduction in Children and Adolescents (Expert Panel, 2011)
 Total Cholesterol≥170 mg/dL≥190 mg/dL
 HDL≤ 40 mg/dLAll ages
 Triglycerides≥ 75 mg/dLages 2–9 years
≥ 90 mg/dLages 10–19 years
≥ 115 mg/dLages ≥20 years
 SBP≥ 95th %tile for age, sex and heightages 2–17 yearsFourth Report on the Diagnosis, Evaluation, and Treatment of High Blood Pressure in Children and Adolescents (2004)
Seventh Report of the Joint National Committee on the Prevention, Detection, Evaluation, and Treatment of High Blood Pressure for adults (2003)
≥ 140 mmHgages ≥18 years
 DBP≥ 95th %tile for age, sex and heightages 2–17 years
≥ 90 mmHgages ≥18 years
 Multiple risk factor variableAbnormal values for glucose, LDL, HDL, CRP or BP or taking medications for diabetes, dyslipidemia or hypertension