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Table 4 Bivariate and multivariate analysis for factors associated with time to mortality (Cox regression analysis) among children with severe acute malnutrition admitted to Mulago hospital

From: Mortality among children under five years admitted for routine care of severe acute malnutrition: a prospective cohort study from Kampala, Uganda

VariableDead n/N (%)Bivariate analysisp valueMultivariate analysisp value
UHR (95% CI)AHR (95% CI)
Sex
 Male38/160 (23.8)1   
 Female29/106 (27.4)1.2 (0.7–1.9)0.505  
Diarrhea
 No24/116 (20.7)1 1 
 Yes43/150 (28.7)1.5 (0.9–2.4)0.1421.1 (0.7–1.9)0.684
Fever
 No28/127 (22.1)1   
 Yes39/139 (28.1)1.3 (0.8–2.1)0.339  
Temperature (°C)
 Normal38/175 (21.7)1   
 Hypothermia2/9 (22.2)1.02 (0.2–4.2)0.977  
 Hyperthermia26/75 (34.7)1.6 (1–2.7)0.059  
Dehydration
 No33/168 (19.6)1   
 Yes34/98 (34.7)2 (1.2–3.2)0.005  
Oral thrush
 No43/206 (20.9)1   
 Yes24/60 (40)2.1 (1.2–3.4)0.005  
Edema
 No44/144 (30.6)1 1 
 Yes23/122 (18.9)0.6 (0.4–1)0.0501 (0.6–1.8)0.951
Visible Wasting
 No10/57 (17.5)1 1 
 Yes57/209 (27.3)1.6 (0.8–3.1)0.1681.3 (0.6–2.6)0.493
Signs of vitamin A deficiency
 No65/262 (24.8)1 1 
 Yes2/4 (50)3.2 (0.8–13.3)0.1021.5 (0.3–7.5)0.601
Diagnosis of pneumonia
 No33/162 (20.4)1 1 
 Yes34/104 (32.7)1.7 (1.1–2.8)0.0271.5 (0.9–2.5)0.153
HIV status
 Negative52/234 (22.2)1 1 
 Positive15/32 (46.9)2.1 (1.2–3.8)0.012.2 (1.2–4.2)0.014
Blood culture
 No growth61/258 (23.6)1 1 
 Growth6/8 (75)6.3 (2.7–14.9)0.0009 (3.4–23.4)< 0.001
Glucose levels
  < 34/10 (40)2.4 (0.9–6.7)0.0972.1 (0.7–6.3)0.163
 3- < 8.341/211 (19.4)2.9 (1.7–4.8)0.0001 
  ≥ 8.322/43 (51.2)  1.5 (0.9–2.7)0.154
GFR
  ≥ 9023/144 (16)1 1 
 60- < 9012/55 (21.8)1.4 (0.7–2.8)0.3401.6 (0.8–3.3)0.188
 30- < 6019/46 (41.3)3.1 (1.7–5.7)0.0003.2 (1.7–6.3)0.001
  < 3012/16 (75)6.5 (3.2–13.1)0.0005.2 (2.3–11.4)< 0.001
Potassium (mmol/dl)
  ≥ 3.543/195 (22.1)1 1 
  < 3.523/(34.9)1.7 (1–2.8)0.0461.3 (0.8–2.3)0.336
Hemoglobin level (g/dl)
  ≥ 755/226 (24.3)1   
  < 712/36 (33.3)1.3 (0.7–2.5)0.351