Table 6 Relationship between dependent variables (FEV1, FVC, number of lung lobes, chest CT score, BSI, FACED and e-FACED) and selected characteristics. Coefficients and 95% confidence intervals (CI) calculated with univariate and multivariable linear regression models
| Crude slopes(95% CI) | |||||||
|---|---|---|---|---|---|---|---|
| Independent variables | FEV1(%) Predicted value | FVC (%) Predicted value | Number of lung lobes | Chest CT score | BSI | FACED | e- FACED |
| Gender(males vs females) | + 8.9 (− 5.3, + 23.2) | + 0.1 (− 13.2, + 13.3) | - 0.6 (− 1.4, + 0.2) | - 4.6 (− 10.3, + 1.0) | - 1.6 (− 4.0, + 0.7) | - 0.6 (− 1.2, + 0.05) | - 0.8 (− 1.9, + 0.3) |
| Age(10 years) | - 5.4 (− 9.2, − 1.6) | - 5.1 (− 8.6, − 1.6) | + 0.4 (+ 0.2, + 0.6) | + 2.9 (+ 1.5, + 4.3) | + 0.9 (+ 0.3, + 1.5) | + 0.2 (+ 0.03, + 0.4) | + 0.4 (+ 0.1, + 0.7) |
| BMI(Kg/m2) | - 1.3 (− 2.9, + 0.3) | - 1.2 (− 2.7, + 0.4) | + 0.2 (+ 0.1, + 0.2) | + 1.0 (+ 0.4, + 1.5) | + 0.3 (+ 0.1, + 0.6) | + 0.1 (+ 0.03, + 0.2) | + 0.2 (+ 0.1, + 0.3) |
| PA colonization Yes (# 15) vs No (# 43) | - 4.6 (− 19.9, + 10.7) | - 2.0 (− 16.0, + 12.0) | + 1.0 (+ 0.1, + 1.9) | + 7.9 (+ 1.8, + 14.0) | + 4.2 (+ 1.9, + 6.5) | + 1.3 (+ 0.7, + 1.9) | + 1.7 (+ 0.6, + 2.8) |
| Exacerbations ≥ 2 (# 36) vs < 2 (# 22) | - 15.4 (− 30.3, − 0.5) | - 8,2 (− 22.6, + 6.1) | + 1.4 (+ 0.7, + 2.6) | + 9.6 (+ 4.2, + 15.0) | + 4.4 (+ 2.3, + 6.6) | + 0.9 (+ 0.2, + 1.5) | + 1.8 (+ 0.7, + 2.8) |
| Slopes adjusted for gender, age, BMI, PA colonization, and exacerbations(95% CI) | |||||||
| Independent variables | FEV1(%) Predicted value | FVC (%)Predicted value | Number of lung lobes | Chest CT score | BSI | FACED | e- FACED |
| Gender(males vs females) | + 10.4 (− 3.5, + 24.3) | + 1.0 (− 12.4, + 14.4) | - 0.7 (− 1.3, + 0.1) | - 4.9 (− 9.7, − 0.1) | - 0.9 (− 2.8, + 1.0) | - 0.4 (− 0.9, + 0.1) | - 0.5 (− 1.5, + 0.4) |
| Age(10 years) | - 4.9 (− 9.7, − 0.2) | - 4.9 (− 9.4, − 0.4) | + 0.2 (0.00, + 0.4) | + 1.9 (+ 0.2, + 3.6) | + 0.4 (− 0.3, + 1.1) | + 0.05 (− 0.1, + 0.2) | + 0.1 (− 0.2, + 0.4) |
| BMI(Kg/m2) | - 0.1 (− 2.0, + 1.7) | + 0.03 (− 1.8, + 1.9) | + 0.1 (+ 0.01, + 0.2) | + 0.4 (− 0.3, + 1.0) | + 0.1 (− 0.1, + 0.4) | + 0.1 (− 0.01, + 0.1) | + 0.1 (− 0.03, + 0.2) |
| PA colonization Yes (# 15) vs No (# 43) | + 0.5 (− 14.1, + 15.1) | - 0.7 (− 14.6, + 13.3) | + 0.4 (− 0.4, + 1.1) | + 3.7 (− 1.7, + 9.1) | + 2.8 (+ 0.6, + 4.9) | + 1.0 (+ 0.4, + 1.6) | + 1.1 (0.0, + 2.1) |
| Exacerbations ≥ 2 (# 36) vs < 2 (# 22) | - 10.4 (− 25.2, + 4.4) | - 4.7 (− 19.0, + 9.7) | + 0.7 (+ 0.1, + 1.4) | + 5.2 (+ 0.1, + 10.3) | + 2.9 (+ 0.8, + 5.0) | + 0.4 (− 0.2, + 0.4) | + 1.1 (+ 0.1, + 2.1) |