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Table 3 Difference between adults and children in clinical and laboratory features of FS

From: Phenotypic variability in a child with Felty’s syndrome: a case report

PatientF/M ratioArthritisSplenomegalyLeukopeniaThrombocytopeniaAnemiaHypocomplementemiaAutoantibody
Adults2–3/1commoncommonNeutropenia (Always)RarePresentFrequentcommon
ChildrenAll Fin all sixin all sixNeutropenia (Often)OftenPresentNonethree out of six