Etiological serotype and genotype distributions and clinical characteristics of group B streptococcus-inducing invasive disease among infants in South China

Table 3 Clinical characteristics of infants with serotypes Ia, Ib, and III

Characteristics	Serotype Ia (n = 14)	Serotype Ib (n = 12)	Serotype III (n = 51)	F /χ² value	P
Laboratory data
WBC^a, mean ± SD, 10³/μL	15.44 ± 7.78	23.13 ± 7.24	15.83 ± 8.26	2.747	0.071
Platelets, mean ± SD, 10³/μL	357.71 ± 257.28	437.25 ± 224.59	390.80 ± 218.06	0.401	0.671
Abnormal PCT^b, n (%)	2 (14.29)	3 (25.00)	17 (33.33)	2.230	0.328
CRP^c, mean ± SD, mg/L	32.20 ± 38.84	62.29 ± 75.50	54.84 ± 66.49	0.874	0.421
Clinical feature
Fever presentation, n (%)	7 (50.00)	6 (50.00)	31 (60.78)	0.818	0.664
Respiratory distress^d, n (%)	7 (50.00)	8 (66.67)	15 (29.41)	6.485	0.039
Seizure presentation, n (%)	1 (7.14)	1 (8.33)	4 (7.84)	0.341	1.000*
Pneumonia, n (%)	10 (71.43)	10 (83.33)	31 (60.78)	2.604	0.286
Sepsis, n (%)	8 (57.14)	6 (50.00)	37 (72.55)	2.777	0.249
Purulent meningitis, n (%)	1 (7.14)	3 (25.00)	21 (41.18)	7.268	0.026
Pneumorrhagia, n (%)	0 (0.00)	1 (8.33)	2 (3.92)	1.311	0.471*
Shock, n (%)	1 (7.14)	2 (16.67)	5 (9.80)	0.633	0.729
DIC^e, n (%)	1 (7.14)	1 (8.33)	5 (9.80)	0.108	0.947
Total antibiotic duration, mean ± SD, days	9.57 ± 5.52	9.08 ± 4.36	12.08 ± 5.86	2.071	0.133
Length of stay, median (IQR), days	12.00 (6.00, 14.25)	9.00 (6.00, 14.25)	14.00 (7.00, 15.75)	2.043	0.137
Mortality, n (%)	4 (28.57)	0 (0.00)	2 (3.92)	7.328	0.023*

^a White blood cells, ^bProcalcitonin, ^cC-reactive protein
^dRespiratory distress is manifested by rapid breathing, more than 60 breaths per minute, a rapid heart rate, chest wall retractions, expiratory grunting, nasal flaring, and blue discoloration of the skin during breathing efforts
^eDisseminated intravascular coagulation
*Fisher’s exact test

ISSN: 1471-2431