Diagnostic performance of individual characteristics and anthropometric measurements in detecting elevated serum alanine aminotransferase among children and adolescents

Table 4 The AUC (95% CI) of the ROC curve to express the diagnostic performance of combined individual measurements for detecting elevated ALAT (separately by the diagnostic criteria I and II) in multivariate analyses

Combined measurements	Criterion I (> 30 U/L for boys and > 19 U/L for girls)				Criterion II (> 40 U/L for boys and girls)
Combined measurements	AUC	95% CI	SE	P^*	AUC	95% CI	SE	P^*
Age + gender+height	0.643	0.619–0.668	0.012	< 0.001	0.716	0.679–0.753	0.019	< 0.001
Age + gender+height + weight	0.816	0.795–0.836	0.011	< 0.001	0.858	0.826–0.891	0.016	< 0.001
Age + gender+height + BMI	0.813	0.792–0.834	0.011	< 0.001	0.858	0.826–0.890	0.016	< 0.001
Age + gender+height + BMI-z	0.807	0.785–0.829	0.011	< 0.001	0.856	0.823–0.889	0.017	< 0.001

AUC Area under curve, ALAT Alanine aminotransferase, CI Confidence interval, ROC Receiver operating characteristic, SE Standard error
^* Null hypothesis: true area = 0.5

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