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Table 2 The AUC (95% CI) of the ROC curve to judge the discrimination ability of various individual measurements for detecting elevated ALAT (separately by the criteria I and II) in univariate analyses

From: Diagnostic performance of individual characteristics and anthropometric measurements in detecting elevated serum alanine aminotransferase among children and adolescents

Variable

Criterion I (>  30 U/L for boys and > 19 U/L for girls)

Criterion II (>  40 U/L for boys and girls)

AUC

95% CI

SE

P*

AUC

95% CI

SE

P*

Age

0.608

0.584–0.632

0.012

< 0.001

0.613

0.577–0.649

0.018

< 0.001

Gender

0.490

0.464–0.516

0.013

0.435

0.628

0.593–0.664

0.018

< 0.001

Height

0.622

0.597–0.647

0.013

< 0.001

0.695

0.658–0.732

0.019

< 0.001

Weight

0.779

0.755–0.802

0.012

< 0.001

0.850

0.817–0.882

0.016

< 0.001

BMI

0.789

0.765–0.812

0.012

< 0.001

0.850

0.818–0.882

0.016

< 0.001

Height-z

0.522

0.496–0.547

0.013

0.102

0.514

0.473–0.554

0.021

0.517

BMI-z

0.747

0.722–0.772

0.013

< 0.001

0.822

0.787–0.858

0.018

< 0.001

  1. AUC Area under curve, ALAT Alanine aminotransferase, CI Confidence interval, ROC Receiver operating characteristic, SE Standard error
  2. * Null hypothesis: true area = 0.5