Fig. 2From: Stable clinical course in three siblings with late-onset isolated sulfite oxidase deficiency: a case series and literature reviewAxial T2-weighted imaging (T2WI) and fluid-attenuated inversion recovery (FLAIR) magnetic resonance imaging (MRI) scans from Case 1. a, b, T2 W1 and c, d, FLAIR performed 3 days after disease onset at age 1, showing high signal in the bilateral globus pallidus and substantia nigra (arrows). e-h, Follow-up images 1 year after onset revealed that hyper-signal lesions significantly shrank (arrows). i-l, Lesions on the basal ganglia had almost disappeared and the lesion on the substantia nigra disappeared 5.5 years after the onsetBack to article page