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Table 4 Multivariate Logistic Regression Models Predicting Odds of Neonatal Mortality within 28 days, Based on Assessment at Enrollment

From: Neonatal near-misses in Ghana: a prospective, observational, multi-center study

Variable NameModel 1
(Major Near-Miss Categories)
Pseudo R2 = 0.0982
Model 2
(Aspects of Severe Complications)
Pseudo R2 = 0.0746
Model 3
(Aspects of Interventions)
Pseudo R2 = 0.0982
Model 4
(Aspects of Organ Dysfunction)
Pseudo R2 = 0.1517
Model 5
(Aspects of Investigations)
Psuedo R2 = 0.0133
Model 6
(Model with key predictors from previous models)
Pseudo R2 = 0.2176
Model 7
(Final Model)
Pseudo R2 = 0.2092
ORP value95% CIORP value95% CIORP value95% CIORP value95% CIORP value95% CIORP value95% CIORP value95% CI
Severe Complications2.10.041*1.0–4.1                  
 Apgar Score < 7 at 5 min   1.30.3960.7–2.3               
 Gestational Age < 33 wks   6.4< 0.001*2.2–18.2         3.10.001*1.6–6.03.00.001*1.6–5.9
 Birthweight < 1800 g   0.50.1940.2–1.4               
 Suspected subgaleal bleed   1.30.5760.5–3.5               
 Major congenital abnormality   2.50.0780.9–6.9               
 Axillary temperature < 35 or > 39   1.90.0231.1–3.6         1.70.090.9–3.3   
 Severe jaundice that required blood exchange   2.20.2650.6–8.4               
 Surgery in the first week   1.01.00.9–10.7               
Interventions1.30.5550.5–3.1                  
 Resuscitation at delivery      0.90.7370.4–1.8            
 Resuscitation in NICU      2.00.0690.9–4.1            
 Chest compressions      9.60.007*1.8–50.3      8.30.013*1.6–44.47.20.0191.4–37.5
 IV fluid bolus      1.30.4260.7–2.6            
 Any intubation      0.70.7480.1–6.4            
 Double phototherapy      1.10.9320.3–3.2            
 Double volume exchange blood transfusion      1.10.9430.2–4.5            
 Oxygen therapy      2.00.018*1.1–3.7      0.80.4680.4–1.6   
 Caffeine citrate aminophylline      0.90.8560.4–2.2            
 Thermal protection      1.40.3790.7–3.0            
Organ System Dysfunction3.8< 0.001*1.9–7.2                  
 Cardiovascular         2.10.1740.7–6.4         
 Neurologic         2.9< 0.001*1.6–5.2   2.20.010*1.2–4.32.30.008*1.2–4.2
 Respiratory         4.5< 0.001*2.4–8.3   5.0< 0.001*2.4–10.14.6< 0.001*2.4–8.8
 Renal         1(omitted)   3.00.1520.6–13.8   
 Gastroenterologic         0.40.4350.04–4.2         
Investigations1.60.3270.6–4.2                  
 Hematocrit < 30% in first week            0.70.7740.1–5.8      
 Hemoglobin <10 gd/dl            4.30.044*1.0–18
.4
6.90.003*1.9–24.46.40.004*1.8–22.8
 Blood culture done            0.90.6490.5–1.6      
 Blood culture positive            3.30.1940.5–20.4      
  1. *Significant at p < 0.05