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Table 3 Multiple Logistic regression model of potential risk factors of allergic diseases among participants (OR (95% CI) and P value were presented) (N = 149,726) *

From: Prenatal and neonatal factors involved in the development of childhood allergic diseases in Guangzhou primary and middle school students

Variable#

Allergic asthma

Allergic dermatitis

Allergic rhinitis

Eczema

Age, Year

1.04 (1.03, 1.06) < 0.001

0.93 (0.925, 0.94) < 0.001

/

0.99 (0.98, 0.995) 0.002

Male

1.78 (1.62, 1.95) < 0.001

1.09 (1.04, 1.14) < 0.001

1.18 (1.12, 1.24) < 0.001

1.14 (1.09, 1.20) < 0.001

Birth weight, kg

1.29 (1.15, 1.44) < 0.001

1.28 (1.21, 1.36) < 0.001

1.22 (1.14, 1.31) < 0.001

1.09 (1.02, 1.16) 0.008

Neonatal feeding

 Breast feeding

Reference

Reference

Reference

Reference

 Breast+ formula feeding

1.27 (1.16, 1.40) < 0.001

1.32 (1.26, 1.38) < 0.001

1.35 (1.27, 1.43) < 0.001

1.16 (1.11, 1.23) < 0.001

 Formula feeding

1.08 (0.95, 1.23) 0.230

0.89 (0.83, 0.95) < 0.001

1.11 (1.02, 1.20) 0.014

0.91 (0.84, 0.97) 0.007

Delivery

 Vaginal delivery

Reference

Reference

Reference

Reference

 Cesarean

1.32 (1.21, 1.44) < 0.001

1.17 (1.12, 1.22) < 0.001

1.25 (1.18, 1.32) < 0.001

1.07 (1.01, 1.12) 0.012

  Only child

1.32 (1.21, 1.44) 0.002

1.45 (1.38, 1.51) < 0.001

/

1.30 (1.24, 1.37) < 0.001

Father smoking

 Never smoked

Reference

/

Reference

Reference

 Quit for > 1 year

1.23 (1.06, 1.43) 0.006

/

1.12 (1.02, 1.24) 0.020

1.19 (1.09, 1.30) < 0.001

 Quit for < 1 year

1.10 (0.84, 1.45) 0.486

/

0.94 (0.78, 1.13) 0.520

1.11 (0.95, 1.29) 0.189

 Current smoking

0.91 (0.83, 1.00) 0.038

/

1.06 (1.00, 1.12) 0.039

1.07 (1.02, 1.13) 0.007

  1. OR Odds Ratio, CI Confidence Interval
  2. *: The multiple Logistic regression was conducted among participants who were singletons with normal birth weight (2.5-4 kg) and whose mother had no pregnancy disorder during pregnancy
  3. #: All variables in the Table 1 were included in the simple regression. Variables with P < 0.05 in the simple regression analysis were included in the multiple regression model. The results of simple regression analysis were not listed in the table