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Table 3 Fully adjusted odds ratios for outcomes at 2 years of age (cerebral palsy (CP) and sensory deficiencies (blindness and deafness), and Ages and Stages Questionnaire (ASQ) results below threshold) amongst survivors of babies born at 27–28 weeks’ gestation in medium and high intensity units compared to low intensity units in France in 2011 using indicators constructed in relation to births at 24–25 weeks’ gestation from rates of antenatal steroid exposure, delivery by Caesarean section and neonatal resuscitation in the delivery room

From: Intensity of perinatal care for extremely preterm babies and outcomes at a higher gestational age: evidence from the EPIPAGE-2 cohort study

ModelMedium intensityHigh intensity
 OR(95% CI)OR(95% CI)
CP and sensory disability (among survivors)
Indicator created from rates of:
Antenatal steroid exposure1.10(0.35 – 3.42)1.16(0.44 – 3.01)
Delivery by Caesarean section0.98(0.40 – 2.40)0.49(0.14 – 1.71)
Neonatal resuscitation in the DR1.76(0.59 – 5.25)1.46(0.50 – 4.33)
ASQ below threshold (among survivors)
Indicator created from rates of:
Antenatal steroid exposure0.89(0.50 – 1.60)0.92(0.55 – 1.57)
Delivery by Caesarean section0.83(0.50 – 1.37)0.88(0.50 – 1.55)
Neonatal resuscitation in the DR1.59(0.88 – 2.89)1.19(0.68 – 2.06)
  1. 95% CI: 95% confidence interval. DR = Delivery room. All analyses adjusted for gestational age, multiple status, fetal sex, maternal age, family socioeconomic status, fertility treatment, chorioamnionitis, labour type, social security, small for gestational age and premature rupture of membranes. All analyses used multiple imputation