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Table 2 Clinical characteristics of the whole sample and statistical comparisons of clinical variables between GI and No-GI groups

From: Vocal and motor behaviors as a possible expression of gastrointestinal problems in preschoolers with Autism Spectrum Disorder

Clinical variables

Values

GI

No-GI

p (No-GI vs GI)

Age (years) mean ± SD

4.14 ± 1.08

4.06 (1.05)

4.19 (1.10)

NS

Males n (%)

71 (83.5%)

26 (36.6%)

45 (63.4%)

NS

Females n (%)

14 (16.5%)

4 (28.6%)

10 (71.4%)

NS

ADOS-2

 CSS Social Affect (mean ± SD)

6.43 ± 2.05

6.77 (1.91)

6.29 (2.05)

NS

 CSS Restricted Repetitive Behaviors (mean ± SD)

8.23 ± 1.46

8.43 (1.48)

8.20 (1.45)

NS

 CSS Total (mean ± SD)

7.05 ± 1.85

7.43 (2.01)

6.95 (1.68)

NS

GMDS-ER (65 out of 85 children were evaluable with this test)

 Locomotor (mean ± SD)

71.85 ± 18.53

70.92 (16.19)

72.88 (20.03)

NS

 Personal-Social (mean ± SD)

54.27 ± 20.00

48.96 (17.48)

57.55 (20.72)

NS

 Hearing and Speech (mean ± SD)

46.03 ± 22.38

42.87 (20.20)

47.07 (23.32)

NS

 Eye-Hand Coordination (mean ± SD)

66.64 ± 22.13

62.32 (20.07)

67.72 (24.34)

NS

 Performance (mean ± SD)

70.75 ± 23.33

67.80 (21.62)

72.26 (24.36)

NS

VABS-II

 Communication (mean ± SD)

50.86 ± 17.79

45.47 (15.22)

54.46 (18.80)

0.0274

 Daily Living (mean ± SD)

66.56 ± 17.07

61.13 (14.29)

69.07 (17.51)

0.0365

 Socialization (mean ± SD)

63.55 ± 15.02

60.93 (13.59)

65.18 (15.83)

NS

 Motor Skills (mean ± SD)

71.88 ± 17.85

69.83 (16.34)

74.71 (17.69)

NS

 Composite Score (mean ± SD)

59.40 ± 19.53

54.40 (18.51)

62.29 (20.03)

NS

CBCL 1.5–5

 Internalizing Problems (mean ± SD)

63.85 ± 9.06

67.48 (7.80)

62.06 (9.04)

0.0065

 Externalizing Problems (mean ± SD)

57.10 ± 9.09

59.07 (7.55)

55.82 (9.61)

NS

 Total Problems (mean ± SD)

62.28 ± 10.51

65.35 (10.02)

60.62 (10.30)

0.0469

RBS-R

 Total Score (mean ± SD)

19.87 ± 13.87

20.07 (13.27)

19.76 (14.29)

NS

 Total Endorsed Score (mean ± SD)

12.76 ± 7.27

13.03 (6.78)

12.62 (7.57)

NS

 Global Score (mean ± SD)

44.18 ± 27.24

60.24 (20.77)

38.12 (27.06)

0.0016

  1. Abbreviations: SD Standard deviation, ADOS-2 Autism Diagnostic Observation Schedule-2, CSS Calibrated Severity Score, GMDS-ER Griffiths Mental Development Scales-Extended Revised, VABS-II Vineland Adaptive Behavior Scales-II, CBCL 1.5–5 Child Behavior Checklist 1.5–5, RBS-R Repetitive Behaviors Scale Revised