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Table 4 Prognostic value of time dependent assessment of perioperative NT-proBNP on prolonged ICU stay (Two stage mixed effects model)

From: Prognostic value of perioperative NT-proBNP after corrective surgery for pediatric congenital heart defects

VariablesEstimateSEORa95% CIp
The first submodel
 Intercept10.740.534.60×1041.64×104 to 1.29×105<0.0001
Time points
 Before surgeryReference    
 1h after surgery0.150.121.160.93 to 1.460.19
 12h after surgery2.630.1213.9011.07 to 17.45<0.0001
 36h after surgery2.070.127.896.29 to 9.91<0.0001
Gender
 FemaleReference    
 Male-0.130.0860.880.74 to 1.040.12
RACHS-1
 I/IIReference    
 III/IV0.520.121.681.32 to 2.14<0.0001
Age, d-0.140.0460.870.79 to 0.950.002
Weight, kg-1.180.120.310.24 to 0.39<0.0001
CPB time, min0.410.101.511.23 to 1.85<0.0001
ACC time, min0.0690.0641.070.95 to 1.210.28
The second submodel
 NT-proBNP levels0.380.111.461.19 to 1.840.001
Time points
 Before surgeryReference    
 1h after surgery0.510.281.670.98 to 2.900.06
 12h after surgery-1.910.760.150.03 to 0.650.01
 36h after surgery1.590.554.921.72 to 14.890.004
Gender
 FemaleReference    
 Male0.090.191.090.76 to 1.600.64
RACHS-1
 I/IIReference    
 III/IV0.870.362.381.20 to 5.020.02
Age, d-1.083.180.346.7×10-4 to 1.82×1020.73
Weight, kg1.030.922.810.45 to 17.250.26
CPB time, min-2.331.750.0970.003 to 3.560.18
ACC time, min-0.693.170.500.001 to 258.160.83
  1. SE standard error, OR odds ratio, CI confidence interval, CPB cardiopulmonary bypass, ACC aorta cross clamp, RACHS-1 Risk Adjustment for Congenital Heart Surgery-1. a-Models adjusted for age, gender, weight, cardiopulmonary bypass time, aorta cross clamp time, and RACHS-1 score