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Table 1 The characteristics of patients with MPHD in the different groups

From: Distinct pituitary hormone levels of 184 Chinese children and adolescents with multiple pituitary hormone deficiency: a single-centre study

 

PSIS

(n = 93)

Hypoplasia (n = 24)

Normal

(n = 10)

Tumor survivor

(n = 57)

P1

P2

P3

P4

P5

P6

N (Males/females)

73/20

19/5

7/3

38/19

      

THt SDS

−0.31 ± 0.76

−0.39 ± 0.66

−0.40 + ±0.39

− 0.26 ± 0.63

0.638

0.714

0.678

0.964

0.406

0.500

CA (years)

9.64 ± 5.04

10.40 ± 4.78

10.16 ± 4.76

8.90 ± 3.70

0.507

0.756

0.233

0.895

0.083

0.263

BA (years)

5.83 ± 4.08

7.62 ± 3.68

9.33 ± 3.69

6.44 ± 3.30

0.053

0.011

0.342

0.226

0.160

0.015

CA/BA

2.27 ± 1.05

1.48 ± 0.39

1.38 ± 0.57

1.49 ± 0.33

≤0.001

0.009

≤0.001

0.557

0.906

0.409

HtSDS

−3.94 ± 1.39

−2.89 ± 1.09

−2.50 ± 1.05

−1.38 ± 1.63

≤0.001

0.003

≤0.001

0.363

≤0.001

0.042

BMISDS

0.16 ± 1.38

0.39 ± 1.34

−0.72 ± 1.74

0.92 ± 1.36

0.468

0.066

≤0.001

0.052

0.111

0.001

Anoxia or asphyxia at birth

61

8

2

0

      

Breech/Foot presentation

46

4

1

0

      

Head presentation

28

15

5

35

      

Cesarean section

19

5

4

22

      

Pituitary Height (mm)

2.59 ± 0.87

2.24 ± 0.87

4.80 ± 1.68

/a

0.083

≤0.001

/

≤0.001

/

/

  1. P1: P-value between PSIS-Group and Hypoplasia -Group. P2: P value between PSIS-Group and Normal-Group. P3: P-value between PSIS-Group and Tumor survivor. P4: P value between Hypoplasia-Group and Normal-Group. P5: P value between Hypoplasia -Group and Tumor survivor-Group. P6: P value between Normal-Group and Tumor survivor-Group
  2. aA large majority of (48/57) tumor survivors were CP survivors, and the normal anatomy of the sellar region was seriously damaged by tumor or the related treatment. So the pituitary height could not be measured in MRI