| M1 Mean (SE) | M2 Mean (SE) | M3 Mean (SE) | P value M1 vs. M2 | P value M1 vs. M3 |
---|---|---|---|---|---|
Day 2 | |||||
 rintSO2 (%, n = 10) | 40 (11) | 38 (7) | 40 (7) | .46 | 1.00 |
 rcSO2 (%, n = 28) | 77 (4) | 77 (3) | 78 (3) | .71 | .43 |
 intFTOE (n = 9) | 0.48 (0.14) | 0.57 (0.14) | 0.47 (0.14) | .24 | .85 |
 cFTOE (n = 27) | 0.13 (0.04) | 0.14 (0.04) | 0.13 (0.04) | .97 | .90 |
Day 3 | |||||
 rintSO2 (%, n = 7) | 37 (11) | 39 (7) | 41 (7) | .58 | .32 |
 rcSO2 (%, n = 25) | 75 (4) | 76 (3) | 76 (3) | .30 | .37 |
 intFTOE (n = 7) | 0.58 (0.14) | 0.48 (0.14) | 0.51 (0.14) | .18 | .31 |
 cFTOE (n = 25) | 0.17 (0.04) | 0.17 (0.04) | 0.16 (0.04) | .80 | .46 |
Day 4 | |||||
 rintSO2 (%, n = 11) | 34 (10) | 34 (7) | 35 (7) | .91 | .59 |
 rcSO2 (%, n = 28) | 73 (4) | 72 (3) | 73 (3) | .48 | .83 |
 intFTOE (n = 11) | 0.65 (0.14) | 0.59 (0.14) | 0.57 (0.14) | .34 | .19 |
 cFTOE (n = 28) | 0.18 (0.04) | 0.20 (0.04) | 0.17 (0.04) | .27 | .67 |
Day 5 | |||||
 rintSO2 (%, n = 12) | 44 (10) | 38 (7) | 35 (7) | .07 | .01* |
 rcSO2 (%, n = 27) | 73 (4) | 72 (3) | 72 (3) | .32 | .19 |
 intFTOE (n = 12) | 0.49(0.14) | 0.58(0.14) | 0.48 (0.14) | .16 | .84 |
 cFTOE (n = 27) | 0.19 (0.04) | 0.21 (0.04) | 0.21 (0.04) | .26 | .27 |
Day 8 | |||||
 rintSO2 (%, n = 12) | 39 (10) | 38 (7) | 35 (7) | .61 | .21 |
 rcSO2 (%, n = 25) | 67 (4) | 71 (3) | 73 (3) | .01* | <.01* |
 intFTOE (n = 12) | 0.59 (0.13) | 0.56 (0.13) | 0.62 (0.14) | .63 | .66 |
 cFTOE (n = 25) | 0.25 (0.04) | 0.22 (0.04) | 0.20 (0.04) | .27 | .03* |
Day 15 | |||||
 rintSO2 (%, n = 15) | 34 (10) | 39 (7) | 38 (7) | .13 | .15 |
 rcSO2 (%, n = 19) | 66 (4) | 64 (3) | 63 (3) | .22 | .09 |
 intFTOE (n = 15) | 0.59 (0.13) | 0.51 (0.13) | 0.58 (0.13) | .17 | .87 |
 cFTOE (n = 19) | 0.28 (0.05) | 0.26 (0.04) | 0.27 (0.04) | .33 | .76 |
Day 22 | |||||
 rintSO2 (%, n = 11) | 48 (10) | 47 (7) | 45 (7) | .67 | .35 |
 rcSO2 (%, n = 14) | 57 (4) | 58 (3) | 58 (3) | .46 | .39 |
 intFTOE (n = 11) | 0.46 (0.14) | 0.45 (0.14) | 0.46 (0.14) | .93 | .90 |
 cFTOE (n = 14) | 0.36 (0.05) | 0.27 (0.05) | 0.33 (0.04) | <.01* | .23 |
Day 29 | |||||
 rintSO2 (%, n = 10) | 44 (11) | 54 (7) | 50 (7) | .01* | .18 |
 rcSO2 (%, n = 12) | 62 (5) | 63 (3) | 62 (3) | .63 | .87 |
 intFTOE (n = 10) | 0.43 (0.14) | 0.40 (0.14) | 0.45 (0.14) | .65 | .78 |
 cFTOE (n = 12) | 0.26 (0.05) | 0.27 (0.05) | 0.28 (0.05) | .71 | .42 |
Day 36 | |||||
 rintSO2 (%, n = 8) | 47 (11) | 49 (7) | 46 (7) | .56 | .84 |
 rcSO2 (%, n = 8) | 65 (5) | 65 (3) | 66 (3) | .80 | .52 |
 intFTOE (n = 8) | 0.40 (0.14) | 0.37 (0.14) | 0.50 (0.14) | .65 | .21 |
 cFTOE (n = 8) | 0.26 (0.05) | 0.26 (0.05) | 0.23 (0.05) | .88 | .37 |