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Table 1 Patient characteristics during the study period

From: The effect of enteral bolus feeding on regional intestinal oxygen saturation in preterm infants is age-dependent: a longitudinal observational study

Study population n = 29
 Boys/Girls 16/13 (65%/45%)
 Gestational age, weeks 28 + 1 (25 + 1–30 + 5)
 Birth weight, g 1025 (580–1495)
 Sets of twins 4 (14%)
 Small-for-gestational-age (P < 10) 6 (21%)
 Head circumference on day of birth, centimetres 25.0 (22.5–29.0)
 Apgar score at 5 min 7 (2–9)
 SNAPPE-II score 28 (0–77)
Intestinal pathologies
 Necrotizing enterocolitis/spontaneous intestinal perforation 4 (14%)
 Sepsis (including suspected sepsis) 22 (76%)
Circulatory failure
 Fluid resuscitation 7 (24%)
 Inotropic treatment 2 (7%)
Respiratory supporta
 Mechanical ventilation 16 (55%)
 Continuous positive airway pressure 27 (93%)
 High flow 7 (24%)
 Low flow or no support 15 (52%)
Cerebral lesions
Germinal matrix haemorrhage-intraventricular haemorrhage
 Grade I 6 (21%)
 Grade II 2 (7%)
 Transient periventricular echodensities 10 (34%)
 Periventricular leukomalacia 13 (45%)
Patent ductus arteriosus
 Expectative policy 7 (24%)
 Ibuprofen treatment 6 (21%)
 Surgical clip 3 (10%)
 Hyperbilirubinemia 23 (79%)
 Anaemia 19 (66%)
Hemoglobin (mmol/L)
 Day 2 9.1 (7.6–11.6)
 Day 3 9.0 (6.5–11.6)
 Day 4 8.6 (6.5–11.9)
 Day 5 8.4 (6.8–11.9)
 Day 8 8.5 (6.9–10.6)
 Day 15 8.2 (6.2–9.7)
 Day 22 8.0 (5.7–8.4)
 Day 29 7.8 (6.2–9.5)
 Day 36 8.3 (6.4–9.8)
Enteral feedinga
 Mother’s milk 24 (83%)
 Preterm formula 20 (69%)
 Donor mother’s milk 10 (34%)
 Infusion rate bolus feeding (mL/min) 3.4 (0.1–60.0)
  1. Abbreviations: SD, standard deviation. SNAPPE-II, Score for Neonatal Acute Physiology - Perinatal Extension II. The data are expressed as median (range) or as numbers (percentages) unless otherwise specified. aThe numbers exceed totals, because a single infant could have several respiratory supports and several types of enteral feeding during the first 36 days after birth
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