Changes of inflammatory mediators and oxidative stress indicators in children with Henoch-Schönlein purpura and clinical effects of hemoperfusion in the treatment of severe Henoch-Schönlein purpura with gastrointestinal involvement in children

Table 3 Changes of blood inflammatory indicators and oxidative stress indicators in each HSP group and healthy control group (⁻x ± s)

	HSP-GI and renal involvement(n = 60)	HSP + GI involvement(n = 60)	HSPN(n = 80)	Healthy group(n = 30)
IL-6(pg/mL)	10.96 ± 1.47^a	18.37 ± 1.84^ab	22.94 ± 3.43^ac	2.31 ± 0.56
TNF-α(pg/mL)	11.10 ± 1.31^a	17.75 ± 2.35 ^ab	22.26 ± 3.35 ^ac	3.56 ± 1.25
MDA(nmol/mL)	2.04 ± 0.12 ^a	2.96 ± 0.18 ^ab	3.33 ± 0.42 ^ac	1.39 ± 0.24
SOD(U/mL)	44.44 ± 1.93 ^a	38.64 ± 2.14 ^ab	34.12 ± 2.73 ^ac	56.84 ± 4.62
T-AOC(U/mL)	8.62 ± 0.73 ^a	6.24 ± 0.63 ^ab	5.31 ± 0.72 ^ac	13.68 ± 1.68

Note: a indicates comparison with the healthy control group, P = 0.00
b indicates comparison with the HSP without GI and renal involvement group, P = 0.000
c indicates comparison with the HSP without GI and renal involvement group and HSP with GI involvement group, P = 0.000

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