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Table 1 Baseline characteristics of the levothyroxine nontreatment and treatment groups

From: Thyroid dysfunction in preterm infants born before 32 gestational weeks

  Nontreatment
N = 145
Treatment
N = 35
p Adjusted p*
Maternal age (years) 32.6 ± 3.3 32.1 ± 3.6 0.408
Gestational age (weeks+days) 27+ 5 ± 2+ 0 27+ 6 ± 2+ 0 0.931
Birth weight (g) 1026 ± 329 935 ± 266 0.133
Male (%) 79 (54.5) 17 (48.6) 0.529
Caesarean section (%) 95 (65.5) 29 (82.9) 0.047
Multiple gestation (%) 46 (31.7) 6 (17.1) 0.088
Antenatal corticosteroids (%) 128 (88.3) 32 (91.4) 0.594
Premature rupture of membrane (%) 70 (48.3) 11 (31.4) 0.072
Pregnancy-induced hypertension (%) 24 (16.6) 14 (40.0) 0.002 0.045
Gestational diabetes (%) 9 (6.2) 0 (0.0) 0.130
Maternal thyroid disease (%) 1 (0.7) 0 (0.0) 1.000
1 min Apgar score 4.0 ± 1.9 3.8 ± 1.9 0.586
5 min Apgar score 6.1 ± 1.7 5.7 ± 1.7 0.274
Respiratory distress syndrome (%) 112 (77.2) 26 (74.3) 0.711
Early-onset sepsis (%) 1 (0.7) 2 (5.7) 0.097
  1. Values are presented as the means±SDs or numbers (%)
  2. *Adjusted for variables including gestational age and birth weight percentile used as categorical variables (23–25 weeks, 26–28 weeks, 29–31 weeks for gestational age; < 33%, 33–67, > 67% for birth weight percentile), cesarean section and maternal pregnancy-induced hypertension