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Table 2 Potential predictors from the Copenhagen Perinatal Cohort and associations with the Overall mean of milestones

From: Predictors of early life milestones: Results from the Copenhagen Perinatal Cohort

 

N

Mean (SD)

Range

ra

FAMILY BACKGROUND

 Parental social status (1 to 8 point scale)

3421

4.5 (1.8)

1–8

−0.04

 Parity (first child, Yes %)

4001

48.9%

First/not first

0.02

 Maternal age

3988

26.6 (6.5)

14–48

0.003

 Paternal age

3886

30.2 (7.6)

16–71

0.02

 Single mother, prenatally (yes %)

3998

23.2%

Yes/No

−0.002

PREGNANCY AND DELIVERY

 Sex (female %)

4009

48.9%

Female/male

−0.18***

 Gestational age (weeks)

3340

39.1 (2.4)

27–46.5

−0.11***

 Birth weight (grams)

3992

3247 (586)

850–5450

−0.09***

 Birth length (cm)

3989

51.0 (2.7)

24–60

−0.07***

 Head circumference at birth (cm)

3734

34.5 (1.7)

25.1–39.7

−0.07***

 BMI at birth

3988

12.4 (1.4)

7.2–17.5

−0.09***

 Mother’s smoking in last trimester (yes %)

3954

45.8%

Yes/no

0.02

 Mother’s attitude towards pregnancy (unwanted %)

3894

45.1%

Wanted/unwanted

0.03

POSTNATAL FACTORS

 Breastfeeding (months)

3432

3.4 (2.8)

0.3–12

− 0.06***

 Mother’s employment (not employed at 1-year)

2750

88.9%

Yes/no

0.02

 Lived in full-time institution at some point in first year (yes %)

3945

7.3%

Yes/no

0.04*

 Daycare institution at some point in the first year (yes %)

3932

10.7%

Yes/no

−0.0004

POSTNATAL GROWTH AND DEVELOPMENT

 Weight increase, first year (kg)

3425

7.1 (1.3)

3–20.6

0.00

 Length increase, first year (cm)

3374

25.1 (3.6)

14–46.5

0.05**

 Head increase, first year (cm)

3193

12.8 (1.7)

5.5–21.3

0.08***

 BMI increase, first year

3359

5.5 (2.0)

−2.7-22.4

0.02

 Weight increase, age 1–3

2849

4.5 (1.4)

−4.1-11.4

0.004

 Length increase, age 1–3

2871

20.4 (3.7)

0–40

−0.03

 Head increase, age 1–3

2880

3.4 (1.2)

0–13.5

0.004

 Overall mean of 1-year milestones

4008

0.05 (0.7)

−2.17-2.99

0.34***

  1. a Pearson correlations were used to evaluate bivariate associations between each predictor and Overall mean of milestones (point-biserial correlation for binary predictors)
  2. *p < 0.05; ** p < 0.01; *** p < 0.001