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Table 3 Distribution of neurodevelopmental disability by antenatal, delivery, and neonatal characteristics, among infants in Iganga-Mayuge HDSS

From: Prevalence and associated factors of neurodevelopmental disability among infants in eastern Uganda: a population based study

Characteristics

Infants without NDD

Infants with NDD

COR (95% CI)

p-value

ANC Attendance

1–3 times

162 (38.1)

17 (27.4)

1.63 (0.90–2.94)

0.103

4+

263 (61.9)

45 (72.6)

  

IPT/Fansidar*

Yes

386 (90.8)

58 (93.5)

0.68 (0.24–1.98)

0.634

No

39 (9.2)

4 (6.5)

  

Tetanus toxoid

Yes

404 (95.1)

59 (95.2)

0.99 (0.28–3.38)

0.970

No

21 (4.9)

3 (4.8)

  

Complications during pregnancy

No

175 (41.2)

24 (38.7)

  

Yes

250 (58.8)

38 (61.3)

1.11 (0.64–1.91)

0.710

Perinatal Factors

Place of delivery

Hospital

222 (52.2)

23 (37.1)

  

Health Centre, private clinic,etc. (Not hospital)

203 (47.8)

39 (62.9)

1.85 (1.07–3.21)

0.026

Mode of delivery

NVD

363 (85.4)

57 (91.9)

  

Breech & C/S

62 (14.6)

5 (8.1)

0.51 (0.19–1.33)

0.234

Duration of labour

< 24 h

323 (76.0)

49 (79.0)

0.84 (0.43–1.61)

0.599

> 24 h

102 (24.0)

13 (21.0)

  

Perinatal complications

None

389 (91.5)

59 (95.2)

0.55 (0.16–1.84)

0.454

Yes

36 (8.5)

3 (4.8)

  

Neonatal and post-neonatal characteristics

Sex of Baby

Male

218 (51.3)

32 (51.6)

0.99 (0.58–1.68)

0.963

Female

207 (48.7)

30 (48.4)

  

Birth weight

> 2.5 kg

350 (95.6)

46 (90.2)

1

 

< 2.5 kg

16 (4.4)

5 (9.8)

2.38 (0.83–6.79)

0.190

Unknown

59 (13.9)

11 (17.7)

1.42 (0.69–2.89)

 

Cried at birth

Yes

374 (94.7)

49 (79.0)

  

No

21 (5.3)

9 (15.5)

3.27 (1.42–7.50)

0.025

Unknown

30 (7.1)

4 (6.5)

  

Home visit after delivery

Yes

136 (32.0)

20 (32.3)

1.01 (0.57–1.79)

0.968

No

289 (68.0)

42 (67.7)

  

Immediate breast feeding at birth

No

100 (23.5)

12 (19.4)

1.28 (0.66–2.50)

0.466

Yes

325 (76.5)

50 (80.6)

  

Exclusive Breast feeding

Yes

105 (24.8)

12 (19.4)

  

No

320 (75.2)

50 (80.7)

1.37 (0.70–2.67)

0.352

Neonatal danger signs

None

211 (49.6)

28 (45.2)

  

Yes

214 (50.3)

34 (54.8)

1.19 (0.70–2.04)

0.509

Post-neonatal complications

None

64 (15.1)

3 (4.8)

  

Yes

322 (75.7)

54 (87.1)

3.58 (1.10–11.80)

0.036

Don’t know

39 (9.2)

5 (8.1)

2.73 (0.60–12.10)

 

Number of times the baby fell sick since birth

< 4

182 (42.8)

15 (24.2)

  

4+

231 (54.4)

45 (72.6)

2.36 (1.28–4.38)

0.006

Unknown

12 (2.8)

2 (3.2)

2.02 (0.41–9.88)

 

Admission to facility

No

313 (73.6)

44 (71.0)

  

Admitted

112 (26.4)

18 (29.0)

1.14 (0.63–2.06)

0.656

  1. Fansidar* = sulphadoxine/pyrimethamine; COR Crude odds ratio; NDD Neurodevelopmental disability