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Table 3 Serum adrenal steroid levels in both the NW and OW/OB groups at different age groups

From: A cross-sectional survey of adrenal steroid hormones among overweight/obese boys according to puberty stage

 

Age group

NW

 

OW/OB

 

P

N

Value

N

Value

 

Pregnenolone (ug/l)

6- < 10 years

370

0.08(0.05–0.12)

111

0.07(0.04–0.11)

0.29

10- < 12 years

120

0.11(0.07–0.18)

135

0.08(0.05–0.13)

0.001

12- < 15 years

218

0.17(0.12–0.23)

73

0.18(0.11–0.29)

0.42

Corticosterone(ug/l)

6- < 10 years

400

1.45 (0.88–2.86)

117

1.47(0.96–3.36)

0.45

10- < 12 years

162

1.44 (0.83–2.98)

148

1.48(0.78–3.11)

0.85

12- < 15 years

234

1.33(0.74–2.76)

87

1.50(0.77–2.98)

0.49

17OH-progesterone (ng/ml)

6- < 10 years

400

0.20 (0.14–0.31)

117

0.32(0.19–0.49)

< 0.001

10- < 12 years

162

0.38 (0.26–0.58)

148

0.41(0.31–0.57)

0.11

12- < 15 years

234

0.57 (0.42–0.81)

87

0.56(0.42–0.79)

0.77

DHEA (ug/l)

6- < 10 years

400

0.57 (0.28–0.96)

117

1.42(0.80–2.11)

< 0.0001

10- < 12 years

162

1.85 (1.26–2.73)

148

2.27(1.58–3.27)

0.004

12- < 15 years

234

3.40 (2.48–4.48)

87

3.51(2.46–5.12)

0.24

Androstenedione (ug/l)

6- < 10 years

400

0.14 (0.10–0.20)

117

0.23(0.15–0.32)

< 0.0001

10- < 12 years

162

0.30 (0.21–0.42)

148

0.36(0.27–0.45)

0.0035

12- < 15 years

234

0.58 (0.40–0.76)

87

0.56(0.40–0.73)

0.51

FT (pg/ml)

6- < 10 years

400

0.87 (0.52–1.22)

117

1.21(0.85–1.69)

< 0.0001

10- < 12 years

162

1.82 (1.42–2.85)

148

2.21(1.56–3.37)

0.02

12- < 15 years

234

19.78 (8.22–34.40)

87

15.26(4.64–25.16)

0.01

SHBG (nmol/L)

6- < 10 years

96

110.9 (86.45–146.15)

25

71.1 (45.75–121.75)

0.002

10- < 12 years

64

102.4 (70.80–157.10)

33

45.10 (32.55–71.00)

< 0.0001

12- < 15 years

103

36.50 (28.00–49.30)

23

36.90 (19.20–55.70)

0.56

  1. Values are presented as median and interquartile range (IQR)
  2. NW normal weight, OW/OB overweight/obese, FT Free testosterone, DHEA Dehydroepiandrosterone. SHBG: Sex hormone-binding globulin